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Início > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Cardiovascular system> Alacepril
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Alacepril

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Origem: China

Cas No: 74258-86-9

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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  • Especificação de produtos
  • Descrição do produto

  • Property

    CAS No.: 74258-86-9 Formula: C20H26N2O5S Molecular Weight: 406.49600

    Description

    Alacepril (INN) is an ACE inhibitor.

    Basic Info

    Chemical Name Alacepril
    Synonyms

    1-(d-3-acetylthio-2-methylpropanoyl)-l-prolyl-l-phenylalanine;
    (S)-N-[1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-prolyl]-L-phenylalanil;
    L-Phenylalanine,1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-L-prolyl;
    1-((S)-3-acetylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine;
    cetapril;
    1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-L-prolyl-L-phenylalanine;
    N-[(S)-3-Acetylthio-2-methylpropanoyl]-L-Pro-L-Phe-OH;
    du1219;
    Cetapfil;
    (s)-l-phenylalanin;
    1-[(S)-3-Acetylthio-2-methylpropanoyl]-L-Pro-L-Phe-OH;

    CAS No. 74258-86-9
    Molecular Formula C20H26N2O5S
    Molecular Weight 406.49600
    PSA 129.08000
    LogP 2.03410

    Properties

    Density 1.281g/cm3
    Boiling Point 679.1ºC at 760 mmHg
    Flash Point 364.5ºC
    Refractive Index 1.581

    Safety Info

    RTECS UO3516500
    WGK Germany 3
    Risk Statements R22
    Hazard Codes Xn

    Synthesis Route

    1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-L-prolyl-L-phenylalanine tert-butyl ester→Alacepril
    S-(3-chloro-2-methyl-3-oxopropyl) ethanethioate+H-PRO-PHE-OH→Alacepril
    S-[(2R)-3-chloro-2-methyl-3-oxopropyl] ethanethioate+H-PRO-PHE-OH→Alacepril

    Precursor

    S-(3-chloro-2-methyl-3-oxopropyl) ethanethioate
    S-[(2R)-3-chloro-2-methyl-3-oxopropyl] ethanethioate
    L-Phenylalanine methyl ester hydrochloride
    1-[(2S)-3-(acetylthio)-2-methyl-1-oxopropyl]-L-prolyl-L-phenylalanine tert-butyl ester

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