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aflatoxin B1

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Origin: China

Cas No: 1162-65-8

Specification: 99%min

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Supply Ability: 50 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 1162-65-8 Formula: C17H12O6 Molecular Weight: 312.27400

    Description

    Aflatoxin B1 is an aflatoxin produced by Aspergillus flavus and A. parasiticus. It is arguably the most potent carcinogen known, and is up to twice as carcinogenic as an equitoxic dose of X-rays. Aflatoxin B1 is a common contaminant in a variety of foods including peanuts, cottonseed meal, corn, and other grains; as well as animal feeds. Aflatoxin B1 is considered the most toxic aflatoxin and it is highly implicated in hepatocellular carcinoma (HCC) in humans. In animals, aflatoxin B1 has also been shown to be mutagenic, teratogenic, and to cause immunosuppression. Several sampling and analytical methods including thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), mass spectroscopy, and enzyme-linked immunosorbent assay (ELISA), among others, have been used to test for aflatoxin B1 contamination in foods. According to the Food and Agriculture Organization (FAO), the worldwide maximum tolerated levels of aflatoxin B1 was reported to be in the range of 1–20 µg/kg in food, and 5–50 µg/kg in dietary cattle feed in 2003.

    Basic Info

    Chemical Name aflatoxin B1
    Synonyms

    Aflatoxin B1, crystalline;
    Aflatoxin B1 Crystalline;
    AFLATOXIN B1;

    CAS No. 1162-65-8
    Molecular Formula C17H12O6
    Molecular Weight 312.27400
    PSA 74.97000
    LogP 2.27650

    Properties

    Melting Point 268-269 °C

    Safety Info

    Safety Statements 53-45-36-26-16-24-7
    RIDADR UN 3462 6.1/PG 1
    Risk Statements R45; R46; R26/27/28; R36; R20/21/22; R11; R65; R48/23/24/25; R36/38; R39/23/24/25; R23/24/25

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 4800 ug/kg 1.Details of toxic effects not reported other than lethal dose value
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - rat 6 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Unreported LD50 - Lethal dose, 50 percent kill Rodent - rat 6 mg/kg 1.Details of toxic effects not reported other than lethal dose value

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