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aflatoxin B1

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начало: Китай

Кас Но: 1162-65-8

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 50 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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CAS No.: 1162-65-8 Formula: C17H12O6 Molecular Weight: 312.27400

Description

Aflatoxin B1 is an aflatoxin produced by Aspergillus flavus and A. parasiticus. It is arguably the most potent carcinogen known, and is up to twice as carcinogenic as an equitoxic dose of X-rays. Aflatoxin B1 is a common contaminant in a variety of foods including peanuts, cottonseed meal, corn, and other grains; as well as animal feeds. Aflatoxin B1 is considered the most toxic aflatoxin and it is highly implicated in hepatocellular carcinoma (HCC) in humans. In animals, aflatoxin B1 has also been shown to be mutagenic, teratogenic, and to cause immunosuppression. Several sampling and analytical methods including thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), mass spectroscopy, and enzyme-linked immunosorbent assay (ELISA), among others, have been used to test for aflatoxin B1 contamination in foods. According to the Food and Agriculture Organization (FAO), the worldwide maximum tolerated levels of aflatoxin B1 was reported to be in the range of 1–20 µg/kg in food, and 5–50 µg/kg in dietary cattle feed in 2003.

Basic Info

Chemical Name	aflatoxin B1
Synonyms	Aflatoxin B1, crystalline; Aflatoxin B1 Crystalline; AFLATOXIN B1;
CAS No.	1162-65-8
Molecular Formula	C17H12O6
Molecular Weight	312.27400
PSA	74.97000
LogP	2.27650

Properties

Melting Point	268-269 °C

Safety Info

Safety Statements	53-45-36-26-16-24-7
RIDADR	UN 3462 6.1/PG 1
Risk Statements	R45; R46; R26/27/28; R36; R20/21/22; R11; R65; R48/23/24/25; R36/38; R39/23/24/25; R23/24/25

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	4800 ug/kg	1.Details of toxic effects not reported other than lethal dose value
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	6 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Unreported	LD50 - Lethal dose, 50 percent kill	Rodent - rat	6 mg/kg	1.Details of toxic effects not reported other than lethal dose value