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ADRIAMYCIN, HYDROCHLORIDE

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Origin: China

Cas No: 25316-40-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 25316-40-9 Formula: C27H30ClNO11 Molecular Weight: 579.98000

    Description

    Used as an antineoplastic.

    Basic Info

    Chemical Name ADRIAMYCIN, HYDROCHLORIDE
    Synonyms

    DOX HCl;
    ADR;
    DOX;
    Doxorubicin HCl;
    adriamycin hydrochloride;
    14-hydroxydaunomycin hydrochloride;
    Caely;
    Ardriamycin;
    Doxorubicin (Adriamycin) HCl;
    ADRIACIN;
    Dox hydrochloride;
    Hydroxydaunorubicin hydrochloride;
    CAELYX;
    Adriamycin, hydrochloride;
    FI 106;
    DOX,Hydroxydaunorubicin hydrochloride;
    Doxorubicin (hydrochloride);
    Lipodox;
    Doxorubicin Hydrochloride;
    Doxorubicin (Adriamycin);
    fi6804;

    CAS No. 25316-40-9
    Molecular Formula C27H30ClNO11
    Molecular Weight 579.98000
    PSA 206.07000
    LogP 1.50360

    Properties

    Appearance & Physical State Orange-Red Crystalline Solid
    Boiling Point 810.3ºC at 760 mmHg
    Melting Point 216ºC
    Flash Point 443.8ºC
    Stability Stable at room temperature in closed containers under normal storage and handling conditions.
    Storage Condition 2-8ºC
    Vapor Pressure 9.64E-28mmHg at 25°C

    Safety Info

    RTECS QI9295900
    Safety Statements S53-S45-S36/37/39-S22-S7/9
    HS Code 2941909000
    WGK Germany 3
    Risk Statements R45; R22
    Hazard Codes T+
    Signal Word Danger
    Caution Statement P201; P305 + P351 + P338; P308 + P313
    Symbol GHS07, GHS08
    Hazard Declaration H302; H315; H319; H350

    Synthesis Route

    5,​12-​Naphthacenedione, 10-​[(3-​amino-​2,​3,​6-​trideoxy-​α-​L-​lyxo-​hexopyranosyl)​oxy]​-​8-​(2-​bromoacetyl)​-​7,​8,​9,​10-​tetrahydro-​6,​8,​11-​trihydroxy-​1-​methoxy-​, hydrochloride (1:1)​, (8S,​10S)​-→ADRIAMYCIN, HYDROCHLORIDE
    Daunorubicin hydrochloride(BICINS)→ADRIAMYCIN, HYDROCHLORIDE

    Precursor

    5,​12-​Naphthacenedione, 10-​[(3-​amino-​2,​3,​6-​trideoxy-​α-​L-​lyxo-​hexopyranosyl)​oxy]​-​8-​(2-​bromoacetyl)​-​7,​8,​9,​10-​tetrahydro-​6,​8,​11-​trihydroxy-​1-​methoxy-​, hydrochloride (1:1)​, (8S,​10S)​-
    Daunorubicin hydrochloride(BICINS)

    Downstream Product

    N-Trifluoroacetyldoxorubicin
    doxorubicin
    ADRIAMYCINONE
    (2Z)-2-[2-[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-2-oxoethylidene]butanedioic acid

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