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acetazolamide

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Origin: China

Cas No: 59-66-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
59-66-5
Other Names:
Acetazolamide
MF:
C4H6N4O3S2
EINECS No.:
200-440-5
Place of Origin:
Shandong, China
Type:
Anti-Allergic Agents, Antibiotic and Antimicrobial Agents, Vitamins, Amino Acids and Coenzymes
Grade Standard:
Feed Grade, Medicine Grade, Tech Grade
Usage:
Animal Pharmaceuticals
Brand Name:
xigema
Model Number:
TOP
Purity:
99%min
Product Name:
Acetazolamide
Appearance:
White crystalline powder
Assay:
99%min
MW:
222.25
Certificate:
ISO
Application:
Pharmaceutical raw materials
Shelf life:
2 years
Storage:
Cold Dry Place
Melting point:
256-261°C
Density:
1.610 (estimate)
Packaging&Delivery
Packaging Details
as per customers' requirement.
Port
QINGDAO PORT

Property

CAS No.: 59-66-5 Formula: C4H6N4O3S2 Molecular Weight: 222.24500

Description

Acetazolamide, usually sold under the trade name Diamox in some countries, is a carbonic anhydrase inhibitor that is used for the medical treatment of glaucoma, epileptic seizure, idiopathic intracranial hypertension, altitude sickness, cystinuria, periodic paralysis, central sleep apnea, and dural ectasia. Acetazolamide is a diuretic, and it is available as a generic drug in the United States. Diamox is now available as Diamox Sequels in the United States since the original product is no longer made or sold there.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.

Basic Info

Chemical Name	acetazolamide
Synonyms	Cidamex; Diakarb; Edemox; 5-acetamido-1,3,4-thiadiazole-2-sulphonamide; Acetazolamide; Glupax; Diluran; Donmox; DIACARB; Didoc; Diamox; Acetamide, N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-;
CAS No.	59-66-5
Molecular Formula	C4H6N4O3S2
Molecular Weight	222.24500
PSA	151.66000
LogP	0.99800

Properties

Appearance & Physical State	white to off-white crystalline powder
Density	1.744 g/cm3
Melting Point	256-261ºC
Stability	Sensitive to light.
Storage Condition	Store between 15 and 30ºC (59 and 86F), in a well-closed container, unless otherwise specified by manufacturer.

Safety Info

RTECS	AC8225000
Hazard Class	6.1
Safety Statements	S26
HS Code	2935009090
Packing Group	III
RIDADR	UN 2811
Risk Statements	R36/38
Hazard Codes	Xi
Hazard Declaration	H315; H319
Caution Statement	P305 + P351 + P338
Signal Word	Warning
Symbol	GHS07

Synthesis Route

5-acetamido-1,3,4-thiadiazole-2-sulfonyl chloride→acetazolamide
N-(5-benzylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide→acetazolamide
PSA→acetazolamide+4-[1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-yl]oxy-4-oxobutanoic acid

Precursor

5-acetamido-1,3,4-thiadiazole-2-sulfonyl chloride
PSA
N-(5-benzylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide

Downstream Product

acetic acid
5-Amino-1,3,4-thiadiazole-2-sulfonamide

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