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aceclofenac

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Origin: China

Cas No: 89796-99-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
89796-99-6
Other Names:
ACECLOFENAC-D2
MF:
C16H13Cl2NO4
EINECS No.:
641-844-5
Place of Origin:
Jiangsu, China
Type:
Anesthetic Agents, Vitamins, Amino Acids and Coenzymes, Auxiliaries and Other Medicinal Chemicals
Grade Standard:
Medicine Grade
Brand Name:
KPRX
Model Number:
CAS 89796-99-6
Purity:
99%
Product name:
99% Analgesic 89796-99-6
Appearance:
White powder
Application:
For the treatment of osteoarthritis, rheumatoid arthritis
Name:
Aceclofenac
Description:
non-steroidal anti-inflammatory drug
Keyword:
Anti-inflammatory, analgesic and antipyretic
Packaging&Delivery
Packaging Details
20kg/drum
Pallet can be avialable for bulk order.
Port
shanghai or ningbo
Lead Time:
Quantity(Kilograms) 1 - 100 >100
Est. Time(days) 3 To be negotiated

Property

CAS No.: 89796-99-6 Formula: C16H13Cl2NO4 Molecular Weight: 354.18500

Description

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
It should not be given to people with porphyria or breast-feeding mothers, and is not recommended for children.
It is a cytokine inhibitor. Aceclofenac works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of prostaglandins (chemicals in the body) which cause pain, swelling and inflammation. Aceclofenac is the glycolic acid ester of diclofenac.

Basic Info

Chemical Name	aceclofenac
Synonyms	Acelofenac; Falcol; Tresquim; Aceclofenac; Biofenac; Aceclofar; Preservex; Zerodol; Airtal; PR-82/3; Gerbin;
CAS No.	89796-99-6
Molecular Formula	C16H13Cl2NO4
Molecular Weight	354.18500
PSA	75.63000
LogP	3.98030

Properties

Appearance & Physical State	white or off-white crystalline powder
Density	1.455 g/cm3
Boiling Point	486ºC at 760 mmHg
Melting Point	149-153ºC
Flash Point	247.7ºC
Refractive Index	1.639
Storage Condition	-20ºC Freezer

Safety Info

Safety Statements	S26; S36
HS Code	2922509090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Caution Statement	P273; P301 + P310; P305 + P351 + P338; P501
Hazard Declaration	H301; H319; H410
Symbol	GHS06, GHS09
Signal Word	Danger

Synthesis Route

2-(tert-butoxy)-2-oxoethyl 2-(2-((2,6-dichlorophenyl)amino)phenyl)acetate→aceclofenac
diclofenac sodium→aceclofenac
(2-oxo-2-phenylmethoxyethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate→aceclofenac

Precursor

2-(tert-butoxy)-2-oxoethyl 2-(2-((2,6-dichlorophenyl)amino)phenyl)acetate
diclofenac sodium
(2-oxo-2-phenylmethoxyethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate

Downstream Product

diclofenac
(2-methoxy-2-oxoethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate

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