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8-hydroxy-2'-deoxyguanosine

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Origin: China

Cas No: 88847-89-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

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CAS No.: 88847-89-6 Formula: C10H13N5O5 Molecular Weight: 283.24100

Description

A marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. Can induce differentiation of Friend murine erythroleukemia cells in vitro.

Basic Info

Chemical Name	8-hydroxy-2'-deoxyguanosine
Synonyms	2'-deoxy-7,8-dihydro-8-oxo-guanosine; 7,8-dihydro-8-oxo-2'-deoxyguanosine; 8-Hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxodeoxyguanosine; 2'-Deoxy-8-hydroxyguanosine; 8-oxo-7,8-dihydro-2'-deoxiguanosine; 8-oxo-7-hydrodeoxyguanosine; 8-hydroxydeoxyguanosine; 8-Hydroxy-2’-deoxyguanosine; 8-oxo-7,8-dihydro-2'-deoxyguanosine;
CAS No.	88847-89-6
Molecular Formula	C10H13N5O5
Molecular Weight	283.24100
PSA	159.51000
LogP	-1.37070

Properties

Appearance & Physical State	White solid.
Density	2.25 g/cm3
Melting Point	217-220ºC
Refractive Index	1.955
Storage Condition	2-8ºC

Safety Info

HS Code	2934999090

Synthesis Route

2'-deoxyguanosine→8-HYDROXYGUANOSINE+8-hydroxy-2'-deoxyguanosine
2-amino-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-3H-purin-6-one→8-hydroxy-2'-deoxyguanosine
2'-deoxyguanosine→8-hydroxy-2'-deoxyguanosine

Precursor

2-amino-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-3H-purin-6-one
2'-deoxyguanosine
8-Bromo-2'-deoxyguanosine
Acrolein

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