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2'-deoxyguanosine

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Origin: China

Cas No: 961-07-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
961-07-9
Other Names:
Guanine-2'-deoxyriboside
MF:
C10H13N5O4
EINECS No.:
213-505-8
Place of Origin:
Beijing, China
Type:
Vitamins, Amino Acids and Coenzymes
Grade Standard:
Medicine Grade, Tech Grade
Brand Name:
Yibai
Model Number:
961-07-9
Purity:
98.0~102.0%
Product Name:
2'-Deoxyguanosine monohydrate
Appearance:
white to off white crystalline powder
COA:
avaliable
Assay:
98.0~102.0%
resudue on igniton:
0.5%
Shelf life:
3 Years
Total Impurities:
≤1.0%
Quality:
USP
Grade:
Phamaceutical Grade
Production Capacity:
500kg/month
Packaging&Delivery
Packaging Details
Bulk qty: 25kg/drum, inside two level plastic bags
Small qty: Aluminium bag, inside two level plastic bags
Others: can do your package or split small packages according to your request
Port
Beijing, Shanghai, Shenzhen
Lead Time:
Quantity(Grams) 1 - 20000 >20000
Est. Time(days) 5 To be negotiated

Property

CAS No.: 961-07-9 Formula: C10H15N5O5 Molecular Weight: 285.25700

Description

Deoxyguanosine is composed of the purine nucleobase guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is similar to guanosine, but with one hydroxyl group removed from the 2' position of the ribose sugar (making it deoxyribose). If a phosphate group is attached at the 5' position, it becomes deoxyguanosine monophosphate.

Basic Info

Chemical Name	2'-deoxyguanosine
Synonyms	A-2'-DEOXYGUANOSINE; DEOXYGUANOSINE-2'; 2'-Deoxyguanosinemonohydrate; guaninedeoxyriboside; 2'-DEOXY-D-GUANOSINE; Desoxyguanosine; deoxyguanosine; 2'-Deoxyguanosine monohydrate;
CAS No.	961-07-9
Molecular Formula	C10H15N5O5
Molecular Weight	285.25700
PSA	148.51000
LogP	-1.14060

Properties

Appearance & Physical State	white crystalline powder
Density	2.08g/cm3
Boiling Point	725.5ºC at 760mmHg
Melting Point	300ºC
Refractive Index	-42 ° (C=0.2, 1mol/L NaOH)
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store at RT.

Safety Info

RTECS	MF8760000
Safety Statements	S24/25
HS Code	2934999090
WGK Germany	3

Synthesis Route

1-(2-hydroxy-3-methoxypropyl)guanidine+6,7-dihydroxy-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,7-dihydro-4H-imidazo[1,2-a]purin-9-one→2'-deoxyguanosine+2-amino-1-(2-hydroxy-3-methoxypropyl)-4,5-dihydroimidazole-4,5-diol
cladribine→2'-deoxyguanosine+6-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-2-one
N2-(tetrahydrofuran-2-yl)deoxyguanosine→2-hydroxytetrahydrofuran+2'-deoxyguanosine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	>800 mg/kg	1.Details of toxic effects not reported other than lethal dose value
-	DNA inhibition	-	1 mmol/L	-
-	Cytogenetic analysis	-	500 umol/L	-

Precursor

8,2'-anhydro-8-mercaptoguanosine
(2R,3S,5S)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
N-(9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)picolinamide
GMP

Downstream Product

6-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-2-one
8-hydroxy-2'-deoxyguanosine
cladribine
N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]benzamide

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