Home > Organosilicon Compounds> 7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III

7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III

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Origin: China

Cas No: 149107-84-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 149107-84-6 Formula: C41H64O10Si2 Molecular Weight: 773.11200

Description

Intermediate for the preparation of Docetaxel.

Basic Info

Chemical Name	7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
Synonyms	(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4a,8,13,13-tetramethyl-4,6-bis[(triethylsilyl)oxy]-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one; 7,10-bis-O-triethylsilyl baccatin III; 7,10-diTES 10-deacetylbaccatin III; 7,10-bis(triethylsilyl)-10-deacetylbaccatin III; 7,10-di-triethylsilyl-10-deacetylbaccatin III; 7,10-bis-O-triethylsilyl-10-deacetyl baccatin (III);
CAS No.	149107-84-6
Molecular Formula	C41H64O10Si2
Molecular Weight	773.11200
PSA	137.82000
LogP	7.14080

Properties

Refractive Index	1.542

Synthesis Route

10-deacetylbaccatin III+Chlorotriethylsilane→7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
Chlorotriethylsilane+7-O-(Triethylsilyl)-10-deacetyl Baccatin III→7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III

Precursor

10-deacetylbaccatin III
Chlorotriethylsilane
7-O-(Triethylsilyl)-10-deacetyl Baccatin III

Downstream Product

13-O-trimethylsilyl-7,10-bis-O-triethylsilyl-10-deacetyl baccatin III

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