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Picture of 7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III

7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III

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Origin: China

Cas No: 149107-84-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 149107-84-6 Formula: C41H64O10Si2 Molecular Weight: 773.11200

    Description

    Intermediate for the preparation of Docetaxel.

    Basic Info

    Chemical Name 7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
    Synonyms

    (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4a,8,13,13-tetramethyl-4,6-bis[(triethylsilyl)oxy]-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one;
    7,10-bis-O-triethylsilyl baccatin III;
    7,10-diTES 10-deacetylbaccatin III;
    7,10-bis(triethylsilyl)-10-deacetylbaccatin III;
    7,10-di-triethylsilyl-10-deacetylbaccatin III;
    7,10-bis-O-triethylsilyl-10-deacetyl baccatin (III);

    CAS No. 149107-84-6
    Molecular Formula C41H64O10Si2
    Molecular Weight 773.11200
    PSA 137.82000
    LogP 7.14080

    Properties

    Refractive Index 1.542

    Synthesis Route

    10-deacetylbaccatin III+Chlorotriethylsilane7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III
    Chlorotriethylsilane+7-O-(Triethylsilyl)-10-deacetyl Baccatin III7,10-Bis[O-(triethylsilyl)]-10-deacetyl Baccatin III

    Precursor

    10-deacetylbaccatin III
    Chlorotriethylsilane
    7-O-(Triethylsilyl)-10-deacetyl Baccatin III

    Downstream Product

    13-O-trimethylsilyl-7,10-bis-O-triethylsilyl-10-deacetyl baccatin III

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