Home > Organosilicon Compounds> 7-O-(Triethylsilyl)-10-deacetyl Baccatin III

7-O-(Triethylsilyl)-10-deacetyl Baccatin III

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Origin: China

Cas No: 115437-18-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 115437-18-8 Formula: C35H50O10Si Molecular Weight: 658.85100

Basic Info

Chemical Name	7-O-(Triethylsilyl)-10-deacetyl Baccatin III
Synonyms	10-Deacetyl-7-triethylsilylbaccatin III; 7-O-triethylsilyl-10-deacetyl baccatin III; 7-O-Triethylsilyl-10-desacetylbaccatin III; 7-O-triethylsilyl-10-DAB; 7-triethysilyl-10-deacetylbaccatin III;
CAS No.	115437-18-8
Molecular Formula	C35H50O10Si
Molecular Weight	658.85100
PSA	148.82000
LogP	4.11130

Properties

Refractive Index	1.572

Synthesis Route

10-deacetylbaccatin III+Chlorotriethylsilane→7-O-(Triethylsilyl)-10-deacetyl Baccatin III
7-TES-9,10-diketobaccatin III→7-O-(Triethylsilyl)-10-deacetyl Baccatin III
10-deacetylbaccatin III+tert-butyldimethylsilyl chloride→7-O-(Triethylsilyl)-10-deacetyl Baccatin III

Precursor

10-deacetylbaccatin III
tert-butyldimethylsilyl chloride
13-Acetyl-7-(triethylsilyl)baccatin III
Chlorotriethylsilane

Downstream Product

13-{[(3-t-Boc)-2,2-dimethyl-4S-phenyl-1,3-oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III
10-deacetylbaccatin III
paclitaxel
7,10-MeO-10-DAB

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