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Picture of (6S,8S,9S,10R,13S,14S,17R)-6-chloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(6S,8S,9S,10R,13S,14S,17R)-6-chloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

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Origin: China

Cas No: 52080-57-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 52080-57-6 Formula: C21H25ClO5 Molecular Weight: 392.87300

    Description

    Chloroprednisone is a topical glucocorticoid first reported in 1960. It is a chlorinated derivative of prednisone. The acetate ester prodrug, chloroprednisone 21-acetate, was sold under the brand name Topilan as an anti-inflammatory agent.
    There is little published about chloroprednisone. This may be due to limited activity topically because the skin lacks the necessary activating enzyme 11-Beta hydroxysteroid dehydrogenase. Systemically, this agent's activity on Glucocorticoid receptors may not have competed with agents like Fludrocortisone or Dexamethasone.

    Basic Info

    Chemical Name (6S,8S,9S,10R,13S,14S,17R)-6-chloro-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
    Synonyms

    chloroprednisone;
    Chlorprednisonum;
    Cloroprednisone;
    6|A-Chloro Prednisone;
    Chloroprednisonum;
    6Alpha-Chloro Prednisone;
    Cloroprednisona;
    Cloroprednisone [DCIT];
    UNII-564IBO56IP;

    CAS No. 52080-57-6
    Molecular Formula C21H25ClO5
    Molecular Weight 392.87300
    PSA 91.67000
    LogP 1.98310

    Properties

    Density 1.37g/cm3
    Boiling Point 608.4ºC at 760mmHg
    Flash Point 321.8ºC
    Refractive Index 1.609

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