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6-nitro-1-benzothiophene 1,1-dioxide

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Origin: China

Cas No: 19983-44-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

Property

CAS No.: 19983-44-9 Formula: C8H5NO4S Molecular Weight: 211.19500

Description

Stattic is a Stat3 inhibitor which exhibited potent anti-tumor and induced chemo- and radio-sensitivity in nasopharyngeal carcinoma.

Basic Info

Chemical Name	6-nitro-1-benzothiophene 1,1-dioxide
Synonyms	Stattic; 6-Nitro-benzo<b>thiophen-1,1-dioxid; 6-nitro-1; 6-nitro-1-benzothiophene-1,1-dioxide; Stat three inhibitory compound; STAT3 Inhibitor V,Stattic; Benzo[b]thiophene,6-nitro-,1,1-dioxide; 6-Nitrobenzo[b]thiophene-1,1-dioxide,Stat three inhibitory compound; Benzo[b]thiophene, 6-nitro-, 1,1-dioxide;
CAS No.	19983-44-9
Molecular Formula	C8H5NO4S
Molecular Weight	211.19500
PSA	88.34000
LogP	2.95680

Properties

Density	1.621g/cm3
Boiling Point	461.1ºC at 760mmHg
Melting Point	184ºC
Flash Point	232.6ºC
Refractive Index	1.671
Vapor Pressure	3.04E-08mmHg at 25°C

Safety Info

Safety Statements	S26; S36/37/39
HS Code	2934999090
Risk Statements	R20/21/22
Hazard Codes	Xi; Xn
Hazard Declaration	H302; H315; H319; H335
Signal Word	Warning
Caution Statement	P261; P305 + P351 + P338
Symbol	GHS07

Synthesis Route

THIANAPHTHENE-1,1-DIOXIDE→6-nitro-1-benzothiophene 1,1-dioxide
6-nitro-1,1-dioxo-1λ6-benzo[b]thiophen-5-ylamine→6-nitro-1-benzothiophene 1,1-dioxide
N-(1,1-dioxo-1λ6-benzo[b]thiophen-5-yl)-acetamide→6-nitro-1-benzothiophene 1,1-dioxide

Precursor

6-nitro-1,1-dioxo-1λ6-benzo[b]thiophen-5-ylamine
N-(1,1-dioxo-1λ6-benzo[b]thiophen-5-yl)-acetamide
N-(6-nitro-1,1-dioxo-1λ6-benzo[b]thiophen-5-yl)-acetamide
THIANAPHTHENE-1,1-DIOXIDE

Downstream Product

1,1-dioxo-2,3-dihydro-1-benzothiophen-6-amine
1,1-dioxo-1-benzothiophen-6-amine
2,3-dihydro-1-benzothiophen-6-amine

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