Início > Alcohols> (5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID

(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID

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Origem: China

Cas No: 79516-82-8

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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CAS No.: 79516-82-8 Formula: C20H32O5 Molecular Weight: 352.46500

Basic Info

Chemical Name	(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID
Synonyms	20-hydroxy-leukotriene B4; 20-Hydroxy-LTB4; 20-hydroxyleukotriene; hydroxyleukotriene B4; 20-OH-LTB4; 5S,12R,20-TRIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENOIC ACID;
CAS No.	79516-82-8
Molecular Formula	C20H32O5
Molecular Weight	352.46500
PSA	97.99000
LogP	3.13070

Properties

Density	1.097g/cm3
Boiling Point	581.8ºC at 760 mmHg
Flash Point	319.7ºC
Refractive Index	1.541
Storage Condition	-20ºC

Safety Info

Safety Statements	S16; S26; S36
RIDADR	UN 1170 3/PG 2
Risk Statements	R11; R36/37/38
Hazard Codes	F; Xi

Synthesis Route

(5S,6Z,8E,10E,12R,14Z)-methyl 5,12,20-tris((tert-butyldiphenylsilyl)oxy)icosa-6,8,10,14-tetraenoate→(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID
5(S),12(R),20-tris[(tert-butyldimethylislyl)oxy]-6(Z),8(E),10(E),14(Z)-eicosatetraenoic acid→(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID
Benzoic acid (2Z,4E,6E,10Z)-(1S,8R)-1-(3-ethoxycarbonyl-propyl)-8,16-dihydroxy-hexadeca-2,4,6,10-tetraenyl ester→(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID

Precursor

5-iodo-1-pentanol
1,5-Pentanediol
(5S,6Z,8E,10E,12R,14Z)-methyl 5,12,20-tris((tert-butyldiphenylsilyl)oxy)icosa-6,8,10,14-tetraenoate
Benzoic acid (2Z,4E,6E,10Z)-(1S,8R)-1-(3-ethoxycarbonyl-propyl)-8,16-dihydroxy-hexadeca-2,4,6,10-tetraenyl ester

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