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5-methylcytidine

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Origin: China

Cas No: 2140-61-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 2140-61-6 Formula: C10H15N3O5 Molecular Weight: 257.24300

Description

5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine. It is found in ribonucleic acids of animal, plant, and bacterial origin.

Basic Info

Chemical Name	5-methylcytidine
Synonyms	Cytidine,5-Methyl; 5-METHYLCYTIDINE; 5-Methyl-cytidin; 5-methyl-cytidine;
CAS No.	2140-61-6
Molecular Formula	C10H15N3O5
Molecular Weight	257.24300
PSA	130.83000
LogP	-1.67340

Properties

Appearance & Physical State	Light Yellow Crystals
Density	1.79 g/cm3
Boiling Point	537.5ºC at 760 mmHg
Melting Point	212-215ºC (dec.)(lit.)
Flash Point	278.9ºC
Refractive Index	15 ° (C=2, H2O)
Vapor Pressure	8.5E-14mmHg at 25°C

Safety Info

Safety Statements	S26; S36
HS Code	2934999090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

tert-Butyl ethaneperoxoate+cytidine→1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one+3-methylcytidine
4-methoxy-5-methyl-1-(tri-O-benzoyl-β-D-ribofuranosyl)-1H-pyrimidin-2-one→5-methylcytidine
2',3',5'-tri-O-benzoyl-5-methylcytidine→5-methylcytidine

Precursor

4-methoxy-5-methyl-1-(tri-O-benzoyl-β-D-ribofuranosyl)-1H-pyrimidin-2-one
2',3',5'-tri-O-benzoyl-5-methylcytidine
O2',O3',O5'-tribenzoyl-5-methyl-4-thio-uridine
2',3',5'-Tri-O-benzoyl-5-methyluridine

Downstream Product

5-methylcytosine
N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
5-hydroxymethyl-1-(β-D-ribofuranosyl)cytosine
5-(hydroxymethyl)cytosine

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