Home > Aromatic Compounds> (4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid

(4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid

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Origin: China

Cas No: 84793-07-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
84793-07-7
Other Names:
Fmoc-L-Glu-OtBu-OH
MF:
C24H27NO6
EINECS No.:
N/A
Place of Origin:
China
Type:
Pharmaceutical Intermediates
Purity:
99% min
Brand Name:
Watsonbiotech
Model Number:
Watson
Application:
Pharmaceutical Intermediates
Appearance:
White Powder
Packaging&Delivery
Packaging Details
1kg/foil bag; 25kg/fiber drum
Port
Any port of China
Lead Time:
Quantity(Kilograms) 1 - 25 26 - 100 >100
Est. Time(days) 7 10 To be negotiated

Property

CAS No.: 84793-07-7 Formula: C24H27NO6 Molecular Weight: 425.47400

Basic Info

Chemical Name	(4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
Synonyms	Fmoc-L-Glutamicacid1-tert-butylester; Fmoc-L-Glu-O-t-Bu; FMOC-GLU-OBUT; Fmoc-Glu-OtBu;
CAS No.	84793-07-7
Molecular Formula	C24H27NO6
Molecular Weight	425.47400
PSA	101.93000
LogP	4.49110

Properties

Density	1.232 g/cm3
Boiling Point	638.1ºC at 760 mmHg
Storage Condition	Store at RT.

Safety Info

Hazard Class	8
Safety Statements	S26; S36/37/39
WGK Germany	3
Packing Group	III
RIDADR	UN 3261 8/PG 2
Risk Statements	R34
Hazard Codes	C

Synthesis Route

(S)-4-Amino-5-(tert-butoxy)-5-oxopentanoic acid+N-(9-Fluorenylmethoxycarbonyloxy)succinimide→(4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanedioic acid 5-benzyl ester 1-tert-butyl ester→(4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
Fmoc-Glu(OBzl)-OH→(4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid

Precursor

N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Fmoc-Glu(OBzl)-OH
(S)-4-Amino-5-(tert-butoxy)-5-oxopentanoic acid
L-glutamic acid

Downstream Product

1-O-tert-butyl 5-O-(2,5-dioxopyrrolidin-1-yl) 2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanedioate
(S)-4-Amino-5-(tert-butoxy)-5-oxopentanoic acid
H-γ-GLU-GLU-OH
(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]butanoyl]amino]butanoyl]amino]butanoyl]amino]pentanedioic acid

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