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4-(Pyridin-3-yl)pyrimidin-2-amine

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Origin: China

Cas No: 66521-66-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
66521-66-2
Other Names:
66521-66-2
MF:
C9H8N4
EINECS No.:
1312995-182-4
Place of Origin:
China
Type:
Pharmaceutical Intermediates
Purity:
99.0%min
Brand Name:
sartort
Model Number:
66521-66-2
Application:
nilotinib intermediate
Appearance:
White Powder, White Powder
Packaging&Delivery
Packaging Details
25kg/carton
Port
Any port in china
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 3 To be negotiated

Property

CAS No.: 66521-66-2 Formula: C9H8N4 Molecular Weight: 172.18700

Description

Intermediate in the preparation of Nilotinib.

Basic Info

Chemical Name	4-(Pyridin-3-yl)pyrimidin-2-amine
Synonyms	4-pyridin-3-ylpyrimidin-2-amine;
CAS No.	66521-66-2
Molecular Formula	C9H8N4
Molecular Weight	172.18700
PSA	64.69000
LogP	1.70200

Properties

Density	1.259 g/cm3
Boiling Point	439.9ºC at 760 mmHg
Flash Point	250ºC
Refractive Index	1.641

Safety Info

HS Code	2933990090

Synthesis Route

Guanidine carbonate+1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one→4-(Pyridin-3-yl)pyrimidin-2-amine
2-Amino-4-chloropyrimidine+3-Pyridylboronic acid→4-(Pyridin-3-yl)pyrimidin-2-amine
Guanidine hydrochloride+1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one→4-(Pyridin-3-yl)pyrimidin-2-amine

Precursor

Guanidine carbonate
2-Amino-4-chloropyrimidine
3-Pyridylboronic acid
Guanidine hydrochloride

Downstream Product

4-(Chloromethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
nilotinib
imatinib

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