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(4-methoxyphenyl)hydrazine,hydrochloride

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Origin: China

Cas No: 19501-58-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 19501-58-7 Formula: C7H11ClN2O Molecular Weight: 174.62800

Description

4-Methoxyphenylhydrazine hydrochloride was used in the preparation of 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1,2,4-thiadiazole. It was also used to synthesize diarylpyrazoles as possible cyclooxygenase 2 ((COX-2)) inhibitors.

Basic Info

Chemical Name	(4-methoxyphenyl)hydrazine,hydrochloride
Synonyms	p-methoxy phenyl hydrazine hydrochloride; p-MeO-phenylhydrazine hydrochloride; 4-Anisylhydrazine hydrochloride; 4-Hydrazinoanisole Hydrochloride; 4-Methoxyphenylhydrazine HCl; 4-Methoxyphenylhydrazine Hydrochloride; p-methoxyphenylhydrazine chlorohydrate; (4-Methoxyphenyl)hydrazine hydrochloride; p-anisylhydrazine hydrochloride; 4-OCH3-phenylhydrazine hydrochloride;
CAS No.	19501-58-7
Molecular Formula	C7H11ClN2O
Molecular Weight	174.62800
PSA	47.28000
LogP	2.55610

Properties

Appearance & Physical State	Iron grey to micro red powder
Density	1.15g/cm3
Boiling Point	263.5ºC at 760 mmHg
Melting Point	160-162ºC (dec.)
Flash Point	113.2ºC
Water Solubility	soluble
Stability	Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition	Keep Cold
Vapor Pressure	0.0103mmHg at 25°C

Safety Info

Safety Statements	S36/37
HS Code	29280090
WGK Germany	3
Packing Group	III
RIDADR	UN 2811
Risk Statements	R20/21/22
Hazard Codes	Xn

Synthesis Route

4-methoxybenzenediazonium,chloride→(4-methoxyphenyl)hydrazine,hydrochloride
(3R,4S)-4-hydroxy-2-oxotetrahydrofuran-3-yl 2-(2-(4-methoxyphenyl)hydrazinyl)-2-oxoethanoate→(4-methoxyphenyl)hydrazine,hydrochloride
p-Anisidine→(4-methoxyphenyl)hydrazine,hydrochloride

Precursor

(3R,4S)-4-hydroxy-2-oxotetrahydrofuran-3-yl 2-(2-(4-methoxyphenyl)hydrazinyl)-2-oxoethanoate
4-Methoxybenzenediazonium tetrafluoroborate
1-(4-methoxyphenyl)-1,2-hydrazinedicarboxylic acid bis(2,2,2-trichloroethyl) ester
4-methoxybenzenediazonium,chloride

Downstream Product

2-(4-METHOXYPHENYL)THIOPHENE
indometacin
5-methoxy-2,3,3-trimethyl-1,2-dihydroindole
2-(4-methoxyphenyl)-5-methylpyrazol-3-amine

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