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4-Methoxybenzylchloride

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Origin: China

Cas No: 824-94-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 824-94-2 Formula: C8H9ClO Molecular Weight: 156.60900

    Description

    4-Methoxybenzyl Chloride is used as a reagent in the preparation of pyridone-conjugated monobactam antibiotics with gram-negative activity from Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.

    Basic Info

    Chemical Name 4-Methoxybenzylchloride
    Synonyms

    1-(chloromethyl)-4-methoxybenzene;
    Benzene, 1-(chloromethyl)-4-methoxy-;

    CAS No. 824-94-2
    Molecular Formula C8H9ClO
    Molecular Weight 156.60900
    PSA 9.23000
    LogP 2.43400

    Properties

    Appearance & Physical State Colorless liquid
    Density 1.155
    Boiling Point 117-118ºC (14 mmHg)
    Melting Point -1ºC
    Flash Point 109ºC
    Refractive Index 1.547-1.549
    Water Solubility slowly decomposes
    Storage Condition 2-8ºC

    Safety Info

    Hazard Class 8
    Safety Statements S26-S36/37/39-S45
    HS Code 29093090
    WGK Germany 3
    Packing Group III
    RIDADR UN 3265
    Risk Statements R34
    Hazard Codes C

    Synthesis Route

    (4-Methoxybenzyl)trimethylstannane→1-methoxy-4-[2-(4-methoxyphenyl)ethyl]benzene+Anisic aldehyde
    tributyl-[(4-methoxyphenyl)methyl]stannane→1-methoxy-4-[2-(4-methoxyphenyl)ethyl]benzene+Anisic aldehyde
    tributyl-[(4-methoxyphenyl)methyl]stannane→Anisic aldehyde+4-Methoxybenzylchloride

    Precursor

    anisole
    (4-Methoxybenzyl)trimethylstannane
    Formaldehyde
    tributyl-[(4-methoxyphenyl)methyl]stannane

    Downstream Product

    4-[(dimethylamino)methyl]phenol
    3-(4-methoxyphenyl)-2-phenylpropanoic acid
    6-[(4-methoxyphenyl)methoxy]hexan-1-ol
    1-[(4-methoxyphenyl)methyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole

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