4-hydroxytolbutamide

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Origin: China

Cas No: 5719-85-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 5719-85-7 Formula: C12H18N2O4S Molecular Weight: 286.34700

Description

A metabolite of Tolbutamide. Formed by the cytochrome CYP2CIIC8 and IIC9 subfamily of P450 enzymes.

Basic Info

Chemical Name	4-hydroxytolbutamide
Synonyms	1-Butyl-3-(4-hydroxymethylphenyl)sulfonylurea; Hydroxytolbutamide; 4 hydroxy tolbutamide; hydroxymethyl-TB; [14C]-Hydroxytolbutamide; N-(Butylaminocarbonyl)-4-hydroxymethylbenzenesulfonamide; 4-OH-tolbutamide; Methylhydroxytolbutamide; 1-butyl-3-[4-(hydroxymethyl)phenyl]sulfonylurea; hydroxymethyltolbutamide;
CAS No.	5719-85-7
Molecular Formula	C12H18N2O4S
Molecular Weight	286.34700
PSA	103.88000
LogP	2.82950

Properties

Safety Info

WGK Germany	3

Synthesis Route

methyl 4-(butylcarbamoylsulfamoyl)benzoate→4-hydroxytolbutamide
tolbutamide→4-hydroxytolbutamide
Methyl 4-Sulfamoylbenzoate→4-hydroxytolbutamide

Precursor

Methyl 4-Sulfamoylbenzoate
tolbutamide
methyl 4-(butylcarbamoylsulfamoyl)benzoate
n-butyl isocyanate

Downstream Product

1-butyl-3-(4-formylphenyl)sulfonylurea

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