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4-Hydroxyphenylacetamide

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Origin: China

Cas No: 17194-82-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 17194-82-0 Formula: C8H9NO2 Molecular Weight: 151.16300

Description

4-(Hydroxyphenyl)acetamide is used as an intermediate for the synthesis of Atenolol and various other organic compounds and pharmaceuticals. It is a process impurity for Atenolol

Basic Info

Chemical Name	4-Hydroxyphenylacetamide
Synonyms	2-(4-hydroxyphenyl)acetamide; 4-Hydroxybenzeneacetamide;
CAS No.	17194-82-0
Molecular Formula	C8H9NO2
Molecular Weight	151.16300
PSA	63.32000
LogP	1.12030

Properties

Appearance & Physical State	White to beige powder
Density	1.244g/cm3
Boiling Point	403.9ºC at 760mmHg
Melting Point	175-178ºC
Flash Point	STABILITY
Refractive Index	1.594
Water Solubility	soluble
Stability	Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure	4.22E-07mmHg at 25°C

Safety Info

RTECS	AC3851500
Safety Statements	S24/25
HS Code	2924299090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

4-hydroxyphenylacetic acid→4-Hydroxyphenylacetamide+(3-bromo-4-hydroxyphenyl)acetamide
4'-hydroxyacetophenone→4-Hydroxyphenylacetamide
4-[2-(bromomethyl)-1,3-dioxolan-2-yl]phenol→4-Hydroxyphenylacetamide

Precursor

4-[2-(bromomethyl)-1,3-dioxolan-2-yl]phenol
4'-hydroxyacetophenone
4-acetoxy acetophenone
p-Hydroxyphenyl propanoate

Downstream Product

4-hydroxyphenylacetic acid
L-phenylalanine
D-phenylalanine
N-[(4-hydroxyphenyl)acetyl]-L-phenylalanine

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