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4-Hydroxy-2-(trifluoromethyl)pyridine

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Origin: China

Cas No: 170886-13-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 170886-13-2 Formula: C6H4F3NO Molecular Weight: 163.09700

Basic Info

Chemical Name	4-Hydroxy-2-(trifluoromethyl)pyridine
Synonyms	2-(Trifluoromethyl)-4-Hydroxypyridine; 2-(trifluoromethyl)-1H-pyridin-4-one; 2-(Trifluoromethyl)pyridin-4-ol;
CAS No.	170886-13-2
Molecular Formula	C6H4F3NO
Molecular Weight	163.09700
PSA	33.12000
LogP	1.80600

Properties

Density	1.398g/cm3
Boiling Point	134.256ºC at 760 mmHg
Flash Point	34.997ºC
Refractive Index	1.437
Vapor Pressure	8.157mmHg at 25°C

Safety Info

HS Code	2933399090

Synthesis Route

+1-(3-methylcyctopentyl)-2-piperazinone hydrochloride→4-Hydroxy-2-(trifluoromethyl)pyridine
dimethyl 5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate→4-Hydroxy-2-(trifluoromethyl)pyridine
5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid→4-Hydroxy-2-(trifluoromethyl)pyridine

Precursor

5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid
1-(3-methylcyctopentyl)-2-piperazinone hydrochloride
dimethyl 5-(ethyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2,3-dicarboxylate

Downstream Product

4-Methoxy-2-(trifluoromethyl)pyridine
4-Ethoxy-2-(trifluoromethyl)pyridine
4-Chloro-(2-trifluoromethyl)pyridine
Ethyl 2-(trifluoromethyl)isonicotinate

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