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4-Fluoroacetophenone

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Origin: China

Cas No: 403-42-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
403-42-9
Other Names:
4'-fluoroacetophenone
MF:
C8H7FO
EINECS No.:
NA
Place of Origin:
hebei
Type:
Pharmaceutical Intermediates
Purity:
99%min
Brand Name:
GL
Model Number:
GL
Application:
Pharm Intermediates
Appearance:
White crystalline powder
brand name:
GL
Packaging&Delivery
Packaging Details
Packaging Details:25kg/bag or according to customer's requirement.
Port
Tianjin Qingdao Shanghai

Property

CAS No.: 403-42-9 Formula: C8H7FO Molecular Weight: 138.13900

Description

4’-Fluoroacetophenone is an intermediate used for the synthetic preparation of various pharmaceutical good and agricultural products.

Basic Info

Chemical Name	4-Fluoroacetophenone
Synonyms	Ethanone, 1-(4-fluorophenyl)-; 4’-Fluoroacetophenone; 4'-Fluoroacetophenone; 4‘-Fluoroacetophenone; 1-(4-Fluorophenyl)ethanone;
CAS No.	403-42-9
Molecular Formula	C8H7FO
Molecular Weight	138.13900
PSA	17.07000
LogP	2.02830

Properties

Appearance & Physical State	light yellow clear liquid.
Density	1.138
Boiling Point	196ºC
Melting Point	4ºC
Flash Point	71ºC
Refractive Index	1.51-1.512
Stability	Stable under normal temperatures and pressures.
Storage Condition	Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure	0.888mmHg at 25°C

Safety Info

Safety Statements	S23
HS Code	29147090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Hazard Declaration	H315; H319; H335
Signal Word	Warning
Caution Statement	P261; P305 + P351 + P338
Symbol	GHS07

Synthesis Route

4-Acetylphenylboronic acid→4-Fluoroacetophenone+3'-Fluoroacetophenone
4-Acetylphenylboronic acid, pinacol ester→4-Fluoroacetophenone+3'-Fluoroacetophenone
acetophenone→2'-Fluoroacetophenone+4-Fluoroacetophenone

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Packed	OV-101	120.	1029.	isothermal
Packed	OV-101	130.	1029.7	isothermal
Packed	OV-101	140.	1040.7	isothermal
Packed	OV-101	160.	1047.6	isothermal
Capillary	OV-101	-	1029.	custom temperature program

Precursor

1-Fluoro-4-(1-methylethenyl)benzene
4-Fluorophenylacetylene
n-Butyl vinyl ether
p-(TRIETHOXYSILYL)ACETOPHENONE

Downstream Product

4'-Fluoropropiophenone
2-Bromo-4'-fluoroacetophenone
1-[4-[4-[4-(4-acetylphenoxy)phenyl]phenoxy]phenyl]ethanone
2,2-dibromo-1-(4-fluorophenyl)ethanone

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