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4-Dimethylaminopyridine

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Origin: China

Cas No: 1122-58-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
1122-58-3
Other Names:
DMAP
MF:
C7H10N2
EINECS No.:
214-353-5
Place of Origin:
Shandong, China
Type:
Agrochemical Intermediates
Purity:
99%
Brand Name:
FinerChem
Model Number:
1122-58-3
Application:
Organic Intermediate
Appearance:
White powder
Product name:
4-Dimethylaminopyridine
CAS:
1122-58-3
Appearence:
White powder
Molecular formula:
C7H10N2
Molecular Weight:
122.17
Packaging&Delivery
Packaging Details
Aluminum foil bag for within 10kg
Fiber drum for 10kg and more
Shipping: By air, by sea or by courier (VIP account of TNT, DHL, Fedex and EMS)
Port
Qingdao or Shanghai
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 2 To be negotiated

Property

CAS No.: 1122-58-3 Formula: C7H10N2 Molecular Weight: 122.16800

Description

4-Dimethylaminopyridine (DMAP) is a derivative of pyridine with the chemical formula (CH3)2NC5H4N. This colourless solid is of interest because it is more basic than pyridine, owing to the resonance stabilisation from the NMe2 substituent.
Because of its basicity, DMAP is a useful nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement, Staudinger synthesis of β-lactams and many more. Chiral DMAP analogues are used in kinetic resolution experiments of mainly secondary alcohols and Evans auxiliary type amides.

Basic Info

Chemical Name	4-Dimethylaminopyridine
Synonyms	4-Dimethylaminopyrid; AURORA KA-6495; N-(4-Pyridyl)dimethylamine; 4-Pyridinamine, N,N-dimethyl-; 4-Dimethylaminepyridine; 4-Dimethylami; p-Dimethylaminopyridine; 26DCLPY; DMAP solution; 4-dimethylaminopyridine; 4-(Dimethylamino)pyridine,N,N-Dimethylpyridin-4-amine,DMAP; N,N-Dimethylpyridin-4-amine DMAP; DMAP;
CAS No.	1122-58-3
Molecular Formula	C7H10N2
Molecular Weight	122.16800
PSA	16.13000
LogP	1.14760

Properties

Appearance & Physical State	white to yellow crystalline powder
Density	1.012 g/cm3
Boiling Point	162ºC (50 mmHg)
Melting Point	108-113ºC
Flash Point	110ºC
Refractive Index	n20/D 1.431
Water Solubility	76 g/L (25 ºC)
Stability	Stable. Incompatible with acids, oxidizing agents.
Storage Condition	Store in dark
Vapor Pressure	0.431mmHg at 25°C

Safety Info

RTECS	US8400000
Hazard Class	8
Safety Statements	S26-S28-S36/37/39-S45
HS Code	2933399090
Packing Group	II
WGK Germany	3
RIDADR	UN 1760/2811
Risk Statements	R24/25; R34
Hazard Codes	T
Symbol	GHS06, GHS08
Hazard Declaration	H302; H311; H315; H319; H335; H351
Signal Word	Danger
Caution Statement	P280; P301 + P312 + P330; P302 + P352 + P312; P304 + P340 + P312; P305 + P351 + P338; P337 + P313

Synthesis Route

4-(dimethylamino)-1-((3-nitrophenyl)(phenylimino)methyl)pyridin-1-ium chloride→4-Dimethylaminopyridine+3-NITROBENZANILIDE
2-methyl-3-(4-(dimethylamino)pyridinium)propanal→4-Dimethylaminopyridine+Methacrolein
1-(2-cyanoethyl)-4-(dimethylamino)pyridin-1-ium bromide→4-Dimethylaminopyridine+acrylonitrile

Precursor

N,N-dimethylformamide
guanidine,sulfuric acid
acetylacetone
4-Chloropyridine Hydrochloride

Downstream Product

Boc-3-(1-Naphthyl)-L-alanine
N,N-dimethyl-1-(2,4,6-trinitrophenyl)pyridin-1-ium-4-amine,chloride
1-(2,4-dinitrophenyl)-N,N-dimethylpyridin-1-ium-4-amine,chloride
2-Acetamido-5-nitropyridine

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