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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Cardiovascular system> 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
Picture of 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide

4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide

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Origin: China

Cas No: 14293-44-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 14293-44-8 Formula: C15H15ClN2O4S Molecular Weight: 354.80900

    Description

    Xipamide is a sulfonamide diuretic drug marketed by Eli Lilly under the trade names Aquaphor (in Germany) and Aquaphoril (in Austria). It is used for the treatment of oedema and hypertension.

    Basic Info

    Chemical Name 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
    Synonyms

    4-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide;
    XIPAMIDE;
    Zipix;
    Aquaphoril;
    4-chloro-2',6-dimethyl-5-sulfamoylsalicylanilide;
    Aquaphor;
    Diurexan;
    Xipamid;
    5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide;

    CAS No. 14293-44-8
    Molecular Formula C15H15ClN2O4S
    Molecular Weight 354.80900
    PSA 117.87000
    LogP 4.41620

    Properties

    Density 1.477 g/cm3
    Melting Point 255-256ºC
    Refractive Index 1.652

    Safety Info

    HS Code 2935009090
    Caution Statement P261; P305 + P351 + P338
    Hazard Declaration H315; H319; H335
    Symbol GHS07
    Signal Word Warning

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat 1640 mg/kg 1.Behavioral-ataxia
    2.Behavioral-coma
    3.Lungs, Thorax, or Respiration-respiratory depression
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - rat 320 mg/kg 1.Behavioral-ataxia
    2.Behavioral-coma
    3.Lungs, Thorax, or Respiration-respiratory depression
    Oral LD50 - Lethal dose, 50 percent kill Rodent - mouse 1810 mg/kg 1.Behavioral-ataxia
    2.Behavioral-coma
    3.Lungs, Thorax, or Respiration-respiratory depression

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