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4-(Benzyloxy)pyridine N-oxide

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Origin: China

Cas No: 2683-66-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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CAS No.: 2683-66-1 Formula: C12H11NO2 Molecular Weight: 201.22100

Description

4-Benzyloxypyridine N-Oxide is an intermediate in the synthesis of 4-Hydroxy-1-methyl-2-pyridone, a reactant used in the synthesis of 3-deaza-3-halouracil nucleosides with cytostatic activity in three cancer cell lines.

Basic Info

Chemical Name	4-(Benzyloxy)pyridine N-oxide
Synonyms	4-benzyloxypyridine N-oxide; Pyridine,4-(benzyloxy)-,1-oxide; 4-(benzyloxy)-1$l^{5}-pyridin-1-one; 4-(Benzyloxy)pyridine 1-oxide; 4-benzyloxypyridine 1-oxide; pyridine N-oxide; 4-Benzyloxy-pyridin-1-oxid;
CAS No.	2683-66-1
Molecular Formula	C12H11NO2
Molecular Weight	201.22100
PSA	34.69000
LogP	2.69410

Properties

Appearance & Physical State	White to off-white crystalline powder
Density	1.09 g/cm3
Boiling Point	415.3ºC at 760 mmHg
Melting Point	173-175ºC
Flash Point	205ºC
Refractive Index	1.556
Vapor Pressure	1E-06mmHg at 25°C

Safety Info

Safety Statements	S26-S36/37/39
HS Code	2933399090
WGK Germany	3
Risk Statements	R22; R36/37/38
Hazard Codes	Xn
Symbol	GHS07
Signal Word	Warning
Hazard Declaration	H315; H319; H335
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

4-Nitropyridine N-oxide+benzyl alcohol→4-(Benzyloxy)pyridine N-oxide
4-Chloropyridine N-Oxide+benzyl alcohol→4-(Benzyloxy)pyridine N-oxide
N-(4-Pyridyl)pyridinium chloride hydrochloride→4-(Benzyloxy)pyridine N-oxide

Precursor

benzyl alcohol
benzenecarboperoxoic acid
4-Nitropyridine N-oxide
4-Chloropyridine N-Oxide

Downstream Product

4-BENZYLOXY-2(1 H)-PYRIDONE
4-Hydroxypyridine
4-(Benzyloxy)picolinonitrile
4-phenylmethoxypyridine

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