Home > Organosulfur Compounds> (4-(3-Fluoro-benzyloxy)-3-chlorophenyl)-(6-(2-((2-methanesulphonyl-ethylamino)methyl)-thiazol-4-yl)-quinazolin-4-yl)-amine

(4-(3-Fluoro-benzyloxy)-3-chlorophenyl)-(6-(2-((2-methanesulphonyl-ethylamino)methyl)-thiazol-4-yl)-quinazolin-4-yl)-amine

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Origin: China

Cas No: 388082-81-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 388082-81-3 Formula: C28H27Cl3FN5O3S2 Molecular Weight: 671.03300

Basic Info

Chemical Name	(4-(3-Fluoro-benzyloxy)-3-chlorophenyl)-(6-(2-((2-methanesulphonyl-ethylamino)methyl)-thiazol-4-yl)-quinazolin-4-yl)-amine
Synonyms
CAS No.	388082-81-3
Molecular Formula	C28H27Cl3FN5O3S2
Molecular Weight	671.03300
PSA	142.72000
LogP	9.15130

Properties

Boiling Point	816.5ºC at 760 mmHg
Flash Point	447.6ºC

Synthesis Route

N-{4-[(3-fluorobenzyloxy)]-chlorophenyl}-6-[2-({[2-(methanesulphonyl)ethyl]-[trifluoroacetyl]amino}methyl)-1,3-thiazol-4-yl]-(quinazolin-4-yl)-amine→(4-(3-Fluoro-benzyloxy)-3-chlorophenyl)-(6-(2-((2-methanesulphonyl-ethylamino)methyl)-thiazol-4-yl)-quinazolin-4-yl)-amine
4-Chloro-6-iodoquinazoline→(4-(3-Fluoro-benzyloxy)-3-chlorophenyl)-(6-(2-((2-methanesulphonyl-ethylamino)methyl)-thiazol-4-yl)-quinazolin-4-yl)-amine
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine→(4-(3-Fluoro-benzyloxy)-3-chlorophenyl)-(6-(2-((2-methanesulphonyl-ethylamino)methyl)-thiazol-4-yl)-quinazolin-4-yl)-amine

Precursor

N-(cyanomethyl)-2,2,2-trifluoro-N-(2-(methylthio)ethyl)acetamide
N-{4-[(3-fluorobenzyloxy)]-chlorophenyl}-6-[2-({[2-(methanesulphonyl)ethyl]-[trifluoroacetyl]amino}methyl)-1,3-thiazol-4-yl]-(quinazolin-4-yl)-amine
2-((2-(methylthio)ethyl)amino)acetonitrile
4-Chloro-6-iodoquinazoline

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