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(3S)-3-methylmorpholine

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Origin: China

Cas No: 350595-57-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 350595-57-2 Formula: C5H11NO Molecular Weight: 101.14700

Description

It is useful in preparation of morpholinopyrimidine derivatives as mTOR kinase inhibitors for the treatment of diseases mediated by mTOR kinase and/or one or more PI3K enzymes.

Basic Info

Chemical Name	(3S)-3-methylmorpholine
Synonyms	3S-3-Methylmorpholine; 3-methyl-morpholine; (S)-3-methyl morpholine; (S)-3-Methylmorpholine;
CAS No.	350595-57-2
Molecular Formula	C5H11NO
Molecular Weight	101.14700
PSA	21.26000
LogP	0.32350

Properties

Density	0.891g/cm3
Boiling Point	137.1ºC at 760 mmHg
Refractive Index	1.409

Safety Info

HS Code	2934999090

Synthesis Route

(5S)-5-methylmorpholin-3-one→(3S)-3-methylmorpholine
(3S)-4-benzyl-3-methylmorpholine→(3S)-3-methylmorpholine
(5S)-5-methyl-4-(phenylmethyl)-3-morpholinone→(3S)-3-methylmorpholine

Precursor

(5S)-5-methylmorpholin-3-one
(5S)-5-methyl-4-(phenylmethyl)-3-morpholinone
Acetamide, 2-chloro-N-[(1S)-2-hydroxy-1-methylethyl]-
(3S)-4-benzyl-3-methylmorpholine

Downstream Product

2,7-Dichloro-4-[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidi ne
(S)-4-(3-Chloropropyl)-3-methylmorpholine

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