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(3R)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine,hydrochloride

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Origin: China

Cas No: 910138-96-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 910138-96-4 Formula: C18H20ClNOS Molecular Weight: 333.87600

Description

A napthalenyloxy-substituted amine used in binding studies of human serum albumin along with (S)-Duloxetine. Unlike its enantiomer, it is not a very effective dual serotonin and norepinephrine reuptake inhibitor (SNRI).

Basic Info

Chemical Name	(3R)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine,hydrochloride
Synonyms	I06-1987; UNII-7AKC5EXT4Q;
CAS No.	910138-96-4
Molecular Formula	C18H20ClNOS
Molecular Weight	333.87600
PSA	49.50000
LogP	5.82380

Synthesis Route

(R)-(-)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propylamine→(3R)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine,hydrochloride
(3R)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine→(3R)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine,hydrochloride

Precursor

(R)-(-)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propylamine
(3R)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine

Downstream Product

(S)-duloxetine hydrochloride

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