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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride
Picture of (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride

(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride

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Origin: China

Cas No: 1204818-19-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 1204818-19-8 Formula: C10H11ClF3NO2 Molecular Weight: 269.64800

    Description

    (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride is an intermediate in the synthesis of the new antidiabetic drug Sitagliptine; a trizolopyrazine dipeptidyl peptidase IV inhibitor.

    Basic Info

    Chemical Name (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride
    Synonyms

    CAS No. 1204818-19-8
    Molecular Formula C10H11ClF3NO2
    Molecular Weight 269.64800
    PSA 63.32000
    LogP 2.95070

    Safety Info

    HS Code 2922499990

    Synthesis Route

    (S)-3-((benzyloxycarbonyl)amino)-4-(2,4,5-trifluoro)-4-oxobutanoic acid→(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride
    Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid→(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride
    (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid→(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride

    Precursor

    (S)-3-((benzyloxycarbonyl)amino)-4-(2,4,5-trifluoro)-4-oxobutanoic acid
    (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
    Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid
    1-Bromo-2,4,5-trifluorobenzene

    Downstream Product

    Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid

Hot tags: (3r)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid,hydrochloride, China, manufacturers, suppliers, factory, wholesale, low price, high quality
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