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(3,3-Difluorocyclobutyl)methanol

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Origin: China

Cas No: 681128-39-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 681128-39-2 Formula: C5H8F2O Molecular Weight: 122.11300

Description

(3,3-Difluorocyclobutyl)methanol is an intermediate used to prepare diaminoalkane aspartic protease inhibitors.

Basic Info

Chemical Name	(3,3-Difluorocyclobutyl)methanol
Synonyms	(3,3-DIFLUOROCYCLOBUTYL)METHANOL;
CAS No.	681128-39-2
Molecular Formula	C5H8F2O
Molecular Weight	122.11300
PSA	20.23000
LogP	1.02400

Properties

Density	1.201g/cm3
Boiling Point	130.943ºC at 760 mmHg
Flash Point	32.994ºC
Refractive Index	1.405

Safety Info

HS Code	2906199090

Synthesis Route

3,3-Difluorocyclobutanecarboxylic acid→(3,3-Difluorocyclobutyl)methanol
ethyl 3,3-difluorocyclobutane-1-carboxylate→(3,3-Difluorocyclobutyl)methanol
Ethyl chloroformate+3,3-Difluorocyclobutanecarboxylic acid→(3,3-Difluorocyclobutyl)methanol

Precursor

3,3-difluorocyclobutane-1-carbonitrile
ethyl 3,3-difluorocyclobutane-1-carboxylate
3,3-Difluorocyclobutanecarboxylic acid
3-Methylenecyclobutane-1-Carbonitrile

Downstream Product

3,3-difluorocyclobutane-1-carbaldehyde

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