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3-iodo-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide

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Origin: China

Cas No: 926922-18-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 926922-18-1 Formula: C19H15F3IN3O Molecular Weight: 485.24200

Description

Intermediate in the preparation of Nilotinib.

Basic Info

Chemical Name	3-iodo-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide
Synonyms
CAS No.	926922-18-1
Molecular Formula	C19H15F3IN3O
Molecular Weight	485.24200
PSA	46.92000
LogP	5.43780

Properties

Density	1.61
Melting Point	235-237ºC

Synthesis Route

3-(4-Methyl-1H-Imidazol-1-yl)-5-(Trifluoromethyl)Aniline+3-Iodo-4-methylbenzoyl chloride→3-iodo-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide
3-(4-Methyl-1H-Imidazol-1-yl)-5-(Trifluoromethyl)Aniline→3-iodo-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide
3-(4-Methyl-1H-Imidazol-1-yl)-5-(Trifluoromethyl)Aniline+3-Iodo-4-methylbenzoic acid→3-iodo-4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide

Precursor

3-(4-Methyl-1H-Imidazol-1-yl)-5-(Trifluoromethyl)Aniline
3-Iodo-4-methylbenzoic acid
3-Iodo-4-methylbenzoyl chloride

Downstream Product

nilotinib

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