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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)
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3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)

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Origin: China

Cas No: 260273-82-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 260273-82-3 Formula: C11H11ClN2O2 Molecular Weight: 238.67000

    Basic Info

    Chemical Name 3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)
    Synonyms

    3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;
    3-(2-chloroethyl)-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidine-4-one;
    3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one(Paliperidone);
    3-(2-chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one;
    3-(2-chloroethyl)-2-Methyl-9-hydroxy-4H-pyrido[1,2-a]pyriMidine-4-one;
    9-hydroxy-3-(2-chloroethyl)-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one;

    CAS No. 260273-82-3
    Molecular Formula C11H11ClN2O2
    Molecular Weight 238.67000
    PSA 54.60000
    LogP 1.48980

    Synthesis Route

    2-Amino-3-hydroxypyridine+α-Acetylbutyrolactone→3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)
    3-(2-chloroethyl)-2-methyl-9-phenylmethoxypyrido[1,2-a]pyrimidin-4-one→3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one+3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)
    α-Acetylbutyrolactone+3-phenylmethoxypyridin-2-amine→3-(2-Chloroethyl)-2-methyl-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one (Paliperidone)

    Precursor

    3-(2-chloroethyl)-9-hydroxy-2-methylpyrido[1,2-a]pyrimidin-4-one,hydrochloride
    α-Acetylbutyrolactone
    3-(2-chloroethyl)-2-methyl-9-phenylmethoxypyrido[1,2-a]pyrimidin-4-one
    2-Amino-3-hydroxypyridine

Hot tags: 3-(2-chloroethyl)-2-methyl-9-hydroxy-4h-pyrido[1,2-a]pyrimidin-4-one (paliperidone), China, manufacturers, suppliers, factory, wholesale, low price, high quality
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