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3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione,hydrochloride

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Origin: China

Cas No: 5633-14-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 5633-14-7 Formula: C23H27ClN2O2 Molecular Weight: 398.92600

Description

Benzetimide Hydrochloride has anticholinergic properties and can block pilocarpine-induced lacrimation or salivation at submydriatic dose levels.

Basic Info

Chemical Name	3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione,hydrochloride
Synonyms	Dioxatrine; Spasmentral; R 4929; Benzetimide HCl; EINECS 227-072-8; McN-JR4929; BENZETIMIDE HYDROCHLORIDE;
CAS No.	5633-14-7
Molecular Formula	C23H27ClN2O2
Molecular Weight	398.92600
PSA	52.90000
LogP	4.28900

Properties

Appearance & Physical State	off-white powder
Boiling Point	543.9ºC at 760 mmHg
Flash Point	282.7ºC

Safety Info

Hazard Class	6.1(b)
Packing Group	III
RIDADR	UN 3249
Risk Statements	R22
Hazard Codes	Xn

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intravenous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	37600 ug/kg	1.Behavioral-tremor 2.Behavioral-convulsions or effect on seizure threshold
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	680 mg/kg	1.Peripheral Nerve and Sensation-flaccid paralysis without anesthesia (usually neuromuscular blockage) 2.Sense Organs and Special Senses (Eye)-mydriasis (pupillary dilation) 3.Behavioral-convulsions or effect on seizure threshold
Intravenous	LD50 - Lethal dose, 50 percent kill	Rodent - mouse	46 mg/kg	1.Behavioral-tremor 2.Behavioral-convulsions or effect on seizure threshold

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