Home > Chiral Compounds> (2S,5R)-5-hydroxypiperidine-2-carboxylic acid,hydrochloride

(2S,5R)-5-hydroxypiperidine-2-carboxylic acid,hydrochloride

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Origin: China

Cas No: 824943-40-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 824943-40-0 Formula: C6H12ClNO3 Molecular Weight: 181.61700

Basic Info

Chemical Name	(2S,5R)-5-hydroxypiperidine-2-carboxylic acid,hydrochloride
Synonyms	(2S,5R)-5-hydroxypipecolic acid; (2S)-trans-5-Hydroxy-piperidin-2-carbonsaeure,Hydrochlorid; trans-5-Hydroxy-L-pipecolinsaeure-hydrochlorid; (2S,5R)-5-Hydroxypipecolic acid HCl; (2S,5r)-5-hydroxypipecolic acid hydrochloride; (2S)-trans-5-hydroxy-piperidine-2-carboxylic acid,hydrochloride; (2S,5R)-5-hydroxy-piperidine-2-carboxylic acid hydrochloride;
CAS No.	824943-40-0
Molecular Formula	C6H12ClNO3
Molecular Weight	181.61700
PSA	69.56000
LogP	0.31470

Properties

Boiling Point	374.2ºC at 760 mmHg
Flash Point	180.1ºC

Synthesis Route

1-O-benzyl 2-O-methyl (2S)-3,4-dihydro-2H-pyridine-1,2-dicarboxylate→(2S,5R)-5-hydroxypiperidine-2-carboxylic acid,hydrochloride
1-O-benzyl 2-O-methyl (2S,5R)-5-hydroxy-6-methoxypiperidine-1,2-dicarboxylate→(2S,5R)-5-hydroxypiperidine-2-carboxylic acid,hydrochloride
(S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester→(2S,5R)-5-hydroxypiperidine-2-carboxylic acid,hydrochloride

Precursor

(S)-2-(((benzyloxy)carbonyl)amino)-5-(1,3-dioxolan-2-yl)pentanoic acid
(S)-2-benzyloxycarbonylamino-5-(2-[1,3]dioxolanyl)-pentanoic acid methyl ester
1-O-benzyl 2-O-methyl (2S)-3,4-dihydro-2H-pyridine-1,2-dicarboxylate
(S)-2-AMINO-5-(1,3-DIOXOLAN-2-YL)-PENTANOIC ACID

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