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(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

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Origem: China

Cas No: 192374-14-4

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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  • Especificação de produtos
  • Descrição do produto
  • Property

    CAS No.: 192374-14-4 Formula: C13H19Cl2NO2 Molecular Weight: 292.20100

    Description

    (S,S) Enantiomer metabolite of Bupropion, an antidepressant.

    Basic Info

    Chemical Name (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
    Synonyms

    (S,S)-2-(3'-chlorophenyl)-3,5,5-trimethylmorpholine-2-ol;
    (2S,3S)-hydroxybupropion;
    (RS,RS)-Hydroxybupropion;
    Radafaxine [INN];
    (2S,3S)-2-Hydroxy-2-(3'-chlorophenyl)-3,5,5-trimethylmorpholine;
    (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol;
    Radafaxine;
    (S,S)-Hydroxybupropion;

    CAS No. 192374-14-4
    Molecular Formula C13H19Cl2NO2
    Molecular Weight 292.20100
    PSA 41.49000
    LogP 3.40280

    Properties

    Density 1.144g/cm3
    Boiling Point 386.574ºC at 760 mmHg
    Flash Point 187.594ºC
    Refractive Index 1.523
    Vapor Pressure 0mmHg at 25°C

    Synthesis Route

    2-Amino-2-methyl-1-propanol+(R)-(+)-1-(3-chlorophenyl)-2-hydroxypropan-1-one(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
    1-(3-chlorophenyl)propan-1-one(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
    (Z)-tert-butyl-[1-(3-chlorophenyl)prop-1-enyloxy]dimethylsilane(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

    Precursor

    (R)-1-(3-chlorophenyl)-1-oxopropan-2-yl trifluoromethanesulfonate
    2-Amino-2-methyl-1-propanol
    (R)-(+)-1-(3-chlorophenyl)-2-hydroxypropan-1-one
    1-(3-chlorophenyl)propan-1-one

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