Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 192374-14-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Property

CAS No.: 192374-14-4 Formula: C13H19Cl2NO2 Molecular Weight: 292.20100

Description

(S,S) Enantiomer metabolite of Bupropion, an antidepressant.

Basic Info

Chemical Name	(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Synonyms	(S,S)-2-(3'-chlorophenyl)-3,5,5-trimethylmorpholine-2-ol; (2S,3S)-hydroxybupropion; (RS,RS)-Hydroxybupropion; Radafaxine [INN]; (2S,3S)-2-Hydroxy-2-(3'-chlorophenyl)-3,5,5-trimethylmorpholine; (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol; Radafaxine; (S,S)-Hydroxybupropion;
CAS No.	192374-14-4
Molecular Formula	C13H19Cl2NO2
Molecular Weight	292.20100
PSA	41.49000
LogP	3.40280

Properties

Density	1.144g/cm3
Boiling Point	386.574ºC at 760 mmHg
Flash Point	187.594ºC
Refractive Index	1.523
Vapor Pressure	0mmHg at 25°C

Synthesis Route

2-Amino-2-methyl-1-propanol+(R)-(+)-1-(3-chlorophenyl)-2-hydroxypropan-1-one→(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
1-(3-chlorophenyl)propan-1-one→(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
(Z)-tert-butyl-[1-(3-chlorophenyl)prop-1-enyloxy]dimethylsilane→(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

Precursor

(R)-1-(3-chlorophenyl)-1-oxopropan-2-yl trifluoromethanesulfonate
2-Amino-2-methyl-1-propanol
(R)-(+)-1-(3-chlorophenyl)-2-hydroxypropan-1-one
1-(3-chlorophenyl)propan-1-one

Hot tags: (2s,3s)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol, China, manufacturers, suppliers, factory, wholesale, low price, high quality