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Picture of (2S,3R)-N-hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide

(2S,3R)-N-hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide

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Origin: China

Cas No: 130370-60-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
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  • Property

    CAS No.: 130370-60-4 Formula: C23H31N3O4S2 Molecular Weight: 477.64000

    Description

    Batimastat (INN/USAN, codenamed BB-94) is an anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. It acts as a matrix metalloproteinase inhibitor (MMPI) by mimicking natural MMPI peptides.
    Batimastat was the first MMPI that went into clinical trials. First results of a Phase I trial appeared in 1994. The drug reached Phase III but was never marketed; mainly because it couldn't be administered orally (as opposed to the newer and chemically similar MMPI marimastat), and injection into the peritoneum caused peritonitis.

    Basic Info

    Chemical Name (2S,3R)-N-hydroxy-N'-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide
    Synonyms

    batimastat;
    BB-94;
    Batimastat (BB-94);
    1rm8;

    CAS No. 130370-60-4
    Molecular Formula C23H31N3O4S2
    Molecular Weight 477.64000
    PSA 161.07000
    LogP 4.27030

    Properties

    Density 1.25g/cm3
    Refractive Index 1.604

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