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(2S)-N,N-dimethylpyrrolidine-2-carboxamide

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Origin: China

Cas No: 29802-22-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 29802-22-0 Formula: C7H14N2O Molecular Weight: 142.19900

Description

L-Proline Dimethylamide is a reactant used in the synthesis of fluoromethylsulfonylaminophenyl propanamides as TRPV1 antagonists.

Basic Info

Chemical Name	(2S)-N,N-dimethylpyrrolidine-2-carboxamide
Synonyms	L-N,N-dimethylprolinamide; L-PRO-NME2; N,N-Dimethyl-L-prolinamide; (S)-2-(N,N-dimethylcarbamoyl)pyrrolidine; N,N-dimethyl L-prolineamide; L-proline-N,N-dimethylamide; L-Proline dimethylamide; (S)-N,N-Dimethylpyrrolidine-2-carboxamide; H-Pro-NMe2;
CAS No.	29802-22-0
Molecular Formula	C7H14N2O
Molecular Weight	142.19900
PSA	32.34000
LogP	0.15540

Properties

Density	1.017g/cm3
Boiling Point	250.2ºC at 760mmHg
Flash Point	105.1ºC
Refractive Index	1.475
Storage Condition	-15ºC
Vapor Pressure	0.0219mmHg at 25°C

Safety Info

HS Code	2933990090

Synthesis Route

(3R,7aS)-3-(trichloromethyl)tetrahydropyrrolo[1,2-c]oxazol-1(3H)-one+Dimethylamine→(2S)-N,N-dimethylpyrrolidine-2-carboxamide
(S)-benzyl 2-(dimethylcarbamoyl)pyrrolidine-1-carboxylate→(2S)-N,N-dimethylpyrrolidine-2-carboxamide
(2S)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid→(2S)-N,N-dimethylpyrrolidine-2-carboxamide

Precursor

Dimethylamine
(S)-benzyl 2-(dimethylcarbamoyl)pyrrolidine-1-carboxylate
(2S)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
tert-butyl (2S)-2-(dimethylcarbamoyl)pyrrolidine-1-carboxylate

Downstream Product

N,N-dimethyl-1-[(2S)-pyrrolidin-2-yl]methanamine

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