Home > Aminoacid Compounds> (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid

(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid

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Origin: China

Cas No: 18822-58-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 18822-58-7 Formula: C7H15NO3 Molecular Weight: 161.19900

Basic Info

Chemical Name	(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid
Synonyms	(S)-2-Amino-3-(tert-butoxy)propanoic acid; L-serine tert-butyl ether; H-O-tert-butyl-L-serine; H-Ser(tBu)-OH; H-Ser(But)-OH; O-t-Bu-serine; O-tert-Butyl-L-serine;
CAS No.	18822-58-7
Molecular Formula	C7H15NO3
Molecular Weight	161.19900
PSA	72.55000
LogP	0.91370

Properties

Density	1.08 g/cm3
Boiling Point	266ºC at 760 mmHg
Melting Point	-220ºC (dec.)
Flash Point	114.6ºC
Refractive Index	1.465
Storage Condition	2-8ºC
Vapor Pressure	0.00257mmHg at 25°C

Safety Info

Safety Statements	S22; S24/25
HS Code	2922509090

Synthesis Route

N-Cbz-O-tert-butyl-L-serine→(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid
methyl (2S)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)propanoate→(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid
Z-Ser(O-t-Bu)-OBn→(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid

Precursor

N-Cbz-O-tert-butyl-L-serine
N-(((2-([1,1'-biphenyl]-4-yl)propan-2-yl)oxy)carbonyl)-O-(tert-butyl)-L-serine
Z-Ser(O-t-Bu)-OBn
N-Benzyloxycarbonyl-β-O-tert.butyl-L-serin-[4-nitro-benzylester]

Downstream Product

H-D-SER(TBU)-OH
Fmoc-Ser(tBu)-OPfp
(2S)-3-[(2-methylpropan-2-yl)oxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
(2S)-2-[[(2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoyl]amino]-3-[(2-methylpropan-2-yl)oxy]propanoic acid

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