Home > Chiral Compounds> (2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid

(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid

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Origin: China

Cas No: 52530-60-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 52530-60-6 Formula: C35H45N7O7 Molecular Weight: 675.77400

Basic Info

Chemical Name	(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Synonyms	De-(1-asp-2-arg-3-val)-angiotensin II; Tyrosinyl-isoleucinyl-histidinyl-prolinyl-phenylalanine; Des-(asp(1)-arg(2)-val(3))-angiotensin II; angiotensin (4-8); Tyr-Ile-His-Pro-Phe; (Des-1,2,3)angiotensin II; L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine; angiotensin II (4-8); Ang(4-8); Angiotensin II (4-8) pentapeptide; Angiotensin pentapeptide; tyrosylisoleusylhidstudylprolylphenylalanine;
CAS No.	52530-60-6
Molecular Formula	C35H45N7O7
Molecular Weight	675.77400
PSA	219.84000
LogP	2.85750

Properties

Density	1.316 g/cm3
Boiling Point	1107.2ºC at 760 mmHg
Flash Point	623.4ºC
Refractive Index	1.617
Storage Condition	-15ºC

Synthesis Route

Fmoc-Tyr(t-Bu)-Ile-His(Trt)-Pro-Phe-OH→(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
FMOC-L-Phenylalanine→(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Fmoc-L-Isoleucine→(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid

Precursor

Fmoc-L-Isoleucine
N-Fmoc-N'-trityl-L-histidine
Fmoc-Tyr(t-Bu)-Ile-His(Trt)-Pro-Phe-OH
FMOC-L-Phenylalanine

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