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(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoic acid

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начало: Китай

Кас Но: 86123-10-6

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 50 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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CAS No.: 86123-10-6 Formula: C24H21NO4 Molecular Weight: 387.42800

Description

N-Fmoc-D-phenylalanine is an N-Fmoc-protected form of D-Phenylalanine. D-Phenylalanine is an essential amino acid that serves as a primary precursor for the biosynthesis of catecholamines in the body. D-Phenylalanine is also known to antagonize stress-induced analgesia in humans, and also acts as an anti-enkephalinase agent.

Basic Info

Chemical Name	(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoic acid
Synonyms	Fmoc-(D)-Phe-NH2; (R)-Fmoc-phenylalanine; fmoc-d-phe; N-Fmoc-D-phenylalanine; Fmoc-D-Phe-OH; Fmoc-D-phenylalanine-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine; Fmoc-D-phenylalanine; Fmoc-phenylalanine;
CAS No.	86123-10-6
Molecular Formula	C24H21NO4
Molecular Weight	387.42800
PSA	75.63000
LogP	4.61190

Properties

Appearance & Physical State	white powder
Density	1.276 g/cm3
Boiling Point	620.1ºC at 760 mmHg
Melting Point	181-185ºC
Flash Point	328.8ºC
Storage Condition	2-8ºC

Safety Info

Safety Statements	S22-S24/25
HS Code	2924299090

Synthesis Route

(R)-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl) 2-(((9Hfluoren-9-yl)methoxy)carbonyl)amino-3-phenylpropanoate→(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoic acid
9H-fluoren-9-ylmethyl carbonochloridate+D-phenylalanine→(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoic acid
D-phenylalanine+N-(9-Fluorenylmethoxycarbonyloxy)succinimide→(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoic acid

Precursor

9H-fluoren-9-ylmethyl carbonochloridate
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
D-phenylalanine
(S,S)-pseudoephedrine D-phenylalaninamide

Downstream Product

(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-phenylbutanoic acid
D-phenylalanine
(2R)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoic acid
9-methylidenefluorene

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