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(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid

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начало: Китай

Кас Но: 2419-94-5

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 50 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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Характеристики продукции
Описание продукта

Quick Details
Classification:
Carboxylic Acid
CAS No.:
2419-94-5
MF:
C10H17NO6, C10H17NO6
EINECS No.:
1533716-785-6
Place of Origin:
Shandong, China
Grade Standard:
Medicine Grade
Purity:
98%, 98%
Appearance:
White powder
Brand Name:
Natural Micron Pharm Tech
Model Number:
2419-94-5
Product name:
Boc-L-Glutamic acid
CAS:
2419-94-5
EINECS:
1533716-785-6
MW:
247.25
Melting point:
110 °C (dec.)
Type:
Pharmaceutical Intermediates
Grade:
Medicine Grade
Test Method::
HPLC
Packaging&Delivery
Packaging Details
Packing Method: Aluminium Foil Bags/Drums
Port
Qingdao Port/Shanghai Port
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 5 To be negotiated

Property

CAS No.: 2419-94-5 Formula: C10H17NO6 Molecular Weight: 247.24500

Description

N-Boc-L-glutamic acid is an N-Boc-protected form of L-Glutamic acid. L-Glutamic acid is a nonessential amino acid that is important to the mammalian central nervous system. L-Glutamic acid is also a neurotransmitter for cone photoreceptors in the human brain and is used as a treatment for patients who have liver disease accompanied by encephalopathy (a condition termed ‘hepatic coma’).

Basic Info

Chemical Name	(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid
Synonyms	Boc-Glu-COOH; N-BOC-L-Glu; Boc-L-Glutamicacid; Boc-L-Glu-OH; N-Boc-L-glutamic Acid; Boc-Glu-OH; N-(tert-Butoxycarbonyl)-L-glutaMic Acid; Boc-L-Glutamic acid;
CAS No.	2419-94-5
Molecular Formula	C10H17NO6
Molecular Weight	247.24500
PSA	112.93000
LogP	1.22000

Properties

Appearance & Physical State	White powder with lumps
Density	1.264 g/cm3
Boiling Point	435.9ºC at 760 mmHg
Melting Point	110-113ºC
Flash Point	217.4ºC
Refractive Index	-15 ° (C=1, MeOH)
Storage Condition	2-8ºC
Vapor Pressure	8.13E-09mmHg at 25°C

Safety Info

Safety Statements	S22-S24/25
WGK Germany	3
Risk Statements	R20/21/22
Hazard Codes	Xn

Synthesis Route

Boc-Glu(OCH3)-OtBu→(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid+(2S)-5-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid
Nα,Nca-di-tert-butyloxycarbonylglutamine→tert-Butyl carbamate+(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid
L-glutamic acid+tert-butoxycarbonyl anhydride→(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioic acid

Precursor

N-Boc-L-glutamic Acid 5-Cyclohexyl Ester
tert-butoxycarbonyl anhydride
Boc-Glu(OBzl)-OH
Boc-β-3-picolyl-L-glutamic acid

Downstream Product

(4S)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxo-5-phenylmethoxypentanoic acid
4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
L-glutamic acid
tert-butyl N-[(3S)-2,6-dioxooxan-3-yl]carbamate

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