Home > Organophosphorus Compounds> [[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid

[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid

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Origin: China

Cas No: 104532-17-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 104532-17-4 Formula: C11H14N5O7P Molecular Weight: 359.23200

Basic Info

Chemical Name	[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
Synonyms
CAS No.	104532-17-4
Molecular Formula	C11H14N5O7P
Molecular Weight	359.23200
PSA	192.72000
LogP	0.51810

Properties

Density	2.16g/cm3
Boiling Point	782.9ºC at 760 mmHg
Flash Point	427.3ºC
Refractive Index	1.857
Vapor Pressure	8.15E-26mmHg at 25°C

Synthesis Route

tert-butyldimethylsilyl chloride+2',3'-di-O-p-toluenesulfonyl-2',3'-secoadenosine→[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
5'-O-TRIPHENYLMETHYL-ADENOSINE→[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-carbamoylphosphinic acid→[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid

Precursor

tert-butyldimethylsilyl chloride
5'-O-TRIPHENYLMETHYL-ADENOSINE
(R)-2-((R)-1-(6-amino-9H-purin-9-yl)-2-oxoethoxy)-3-(trityloxy)propanal
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-carbamoylphosphinic acid

Downstream Product

[[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
2-[1-(6-aminopurin-9-yl)ethenoxy]prop-2-en-1-ol

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