Home > Organophosphorus Compounds> [[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid

[[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid

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Origin: China

Cas No: 104532-18-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 104532-18-5 Formula: C11H14N5O8P Molecular Weight: 375.23100

Basic Info

Chemical Name	[[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
Synonyms
CAS No.	104532-18-5
Molecular Formula	C11H14N5O8P
Molecular Weight	375.23100
PSA	213.68000
LogP	-0.42740

Properties

Density	2.3g/cm3
Boiling Point	869.6ºC at 760mmHg
Flash Point	479.7ºC
Refractive Index	1.892
Vapor Pressure	2.69E-32mmHg at 25°C

Synthesis Route

[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid→[[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
5'-O-TRIPHENYLMETHYL-ADENOSINE→[[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-carbamoylphosphinic acid→[[(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid

Precursor

5'-O-TRIPHENYLMETHYL-ADENOSINE
(R)-2-((R)-1-(6-amino-9H-purin-9-yl)-2-oxoethoxy)-3-(trityloxy)propanal
[[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]formic acid
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-carbamoylphosphinic acid

Downstream Product

2-[1-(6-aminopurin-9-yl)ethenoxy]prop-2-en-1-ol

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