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(2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

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Origin: China

Cas No: 95093-99-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 95093-99-5 Formula: C24H26N2O4 Molecular Weight: 406.47400

Description

The optically active isomer of Carvedilol, a nonselective ß-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.

Basic Info

Chemical Name	(2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Synonyms	(+)-Carvedilol; S-(-)-1-(carbazol-4-yloxy)-3-[[2-(O-methoxyphenoxy)ethyl]amino]-2-propanol; (R)-(+)-Carvedilol; (S)-carvedilol;
CAS No.	95093-99-5
Molecular Formula	C24H26N2O4
Molecular Weight	406.47400
PSA	75.74000
LogP	4.12890

Properties

Density	1.25g/cm3
Boiling Point	655.2ºC at 760 mmHg
Melting Point	114-115ºC
Flash Point	350.1ºC
Refractive Index	1.657

Synthesis Route

carvedilol→(2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol+(2S)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol

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