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2,4-Dichloro-5-fluoropyrimidine

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Origin: China

Cas No: 2927-71-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 2927-71-1 Formula: C4HCl2FN2 Molecular Weight: 166.96900

Description

Used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors.

Basic Info

Chemical Name	2,4-Dichloro-5-fluoropyrimidine
Synonyms	5-fluoro-2,4-dichloropyrimidine; 2,4,5,6-TETRAMINOPYRIMIDINE SULFATE; 2,4-dichlor-5-fluorpyrimidin; 2,4-dichloro-5-fluoro pyrimidine; 2,6-dichloro-5-fluororacil;
CAS No.	2927-71-1
Molecular Formula	C4HCl2FN2
Molecular Weight	166.96900
PSA	25.78000
LogP	1.92250

Properties

Appearance & Physical State	Yellow to Orange Crystalline Solid
Boiling Point	80 °C / 16mmHg
Melting Point	37-41 °C(lit.)
Flash Point	223 °F

Safety Info

Safety Statements	S26; S36; S37/39
HS Code	2933599090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Caution Statement	P280; P305 + P351 + P338; P310
Hazard Declaration	H302; H314
Symbol	GHS05, GHS07
Signal Word	Danger

Synthesis Route

5-fluorouracil→2,4-Dichloro-5-fluoropyrimidine
2,4,6-Trichloro-5-fluoropyrimidine→2,4-Dichloro-5-fluoropyrimidine
Bromoethane→2,4-Dichloro-5-fluoropyrimidine

Precursor

5-fluorouracil
Bromoethane
2,4,6-Trichloro-5-fluoropyrimidine

Downstream Product

2-Chloro-5-fluoro-4-methoxypyrimidine
2-chloro-5-fluoro-4-(4-nitroimidazol-1-yl)pyrimidine
5-fluorouracil
2-Chloro-5-fluoro-4-methylpyrimidine

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