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(2,4-Diaminopteridin-6-yl)methanol hydrochloride

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Origin: China

Cas No: 73978-41-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 73978-41-3 Formula: C7H9ClN6O Molecular Weight: 228.63900

Description

Methotrexate intermediate.

Basic Info

Chemical Name	(2,4-Diaminopteridin-6-yl)methanol hydrochloride
Synonyms	(2,4-DIAMINOPTERIDIN-6-YL)METHANOL HYDROCHLORIDE HYDRATE;
CAS No.	73978-41-3
Molecular Formula	C7H9ClN6O
Molecular Weight	228.63900
PSA	123.83000
LogP	1.04090

Properties

Boiling Point	636.5ºC at 760 mmHg
Melting Point	220ºC(lit.)
Flash Point	338.8ºC

Safety Info

Safety Statements	S26; S36
HS Code	2933990090
Risk Statements	R36/37/38
Hazard Codes	Xi
Signal Word	Warning
Caution Statement	P261; P305 + P351 + P338
Symbol	GHS07
Hazard Declaration	H315; H319; H335

Synthesis Route

pyrimidine-2,4,5,6-tetramine+glycerone→(2,4-Diaminopteridin-6-yl)methanol hydrochloride
glycerone+2,4,5,6-Tetraaminopyrimidine sulfate→(2,4-Diaminopteridin-6-yl)methanol hydrochloride

Precursor

glycerone
2,4,5,6-Tetraaminopyrimidine sulfate
pyrimidine-2,4,5,6-tetramine

Downstream Product

2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE
4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoic acid
6-(bromomethyl)pteridine-2,4-diamine

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