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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Cardiovascular system> 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
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2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]

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Origin: China

Cas No: 99200-09-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 99200-09-6 Formula: C22H25F2NO4 Molecular Weight: 405.43500

    Basic Info

    Chemical Name 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
    Synonyms

    Nebivolol;
    (S,R,R,R)-NEBIVOLOL-D2,15N HYDROCHLORIDE;
    Nibivolol;
    rac-nebivolol;
    NEBIVOLOLHCL;
    NEBIVOLOL HYDROCHLORIDE;
    NEBIVOLOL-D4;

    CAS No. 99200-09-6
    Molecular Formula C22H25F2NO4
    Molecular Weight 405.43500
    PSA 70.95000
    LogP 2.75450

    Properties

    Appearance & Physical State Odour
    Density 1.309 g/cm3
    Boiling Point 600.5ºC at 760 mmHg
    Flash Point 316.9ºC
    Refractive Index 1.58

    Synthesis Route

    N-[(S,S)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(R,S)-1-hydroxy-2-(6-fiuoro-chroman-4-one-2-yl)]-amine+N-benzyl-N-[(R,R)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(S,R)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-amine→2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
    6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene→2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]
    Dibenzylamine→2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol]

    Precursor

    N-[(S,S)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(R,S)-1-hydroxy-2-(6-fiuoro-chroman-4-one-2-yl)]-amine
    N-benzyl-N-[(R,R)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(S,R)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-amine
    6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene
    Benzylamine

    Downstream Product

    NEBIVOLOL

Hot tags: 2,2'-iminobis[1-(6-fluoro-3,4-dihydro-2h-chromen-2-yl)ethanol], China, manufacturers, suppliers, factory, wholesale, low price, high quality
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