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20-hydroxy-20-oxo-leukotriene B4

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Origin: China

Cas No: 80434-82-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 80434-82-8 Formula: C20H30O6 Molecular Weight: 366.44900

Basic Info

Chemical Name	20-hydroxy-20-oxo-leukotriene B4
Synonyms	20-carboxy-LTB4; 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid; 5,12-Dihydroxy-delta5,8,11,14-eicosapolyendioic acid; 20-COOH-LTB4; (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid; 20-carboxyleukotriene B4; 20-COOH-Leukotriene B4;
CAS No.	80434-82-8
Molecular Formula	C20H30O6
Molecular Weight	366.44900
PSA	115.06000
LogP	3.22300

Properties

Density	1.151g/cm3
Boiling Point	588.3ºC at 760 mmHg
Flash Point	323.6ºC
Refractive Index	1.548
Storage Condition	-20ºC

Safety Info

Safety Statements	S16; S26; S36
RIDADR	UN 1170 3/PG 2
Risk Statements	R11; R36/37/38
Hazard Codes	F; Xi

Synthesis Route

1-ethyl 20-methyl (5S,6Z,8E,10E,12R,14Z)-5-(benzoyloxy)-12-hydroxyicosa-6,8,10,14-tetraenedioate→20-hydroxy-20-oxo-leukotriene B4
(5S,6Z,8E,10E,12R,14Z)-dimethyl 5,12-bis((tert-butyldiphenylsilyl)oxy)icosa-6,8,10,14-tetraenedioate→20-hydroxy-20-oxo-leukotriene B4
5-HEXYN-1-OL→20-hydroxy-20-oxo-leukotriene B4

Precursor

(9R)-methyl 9-hydroxy-10-((tetrahydro-2H-pyran-2-yl)oxy)dec-6-ynoate
5-HEXYN-1-OL
(R)-methyl 9-((tert-butyldiphenylsilyl)oxy)-10-oxodec-6-ynoate
1-ethyl 20-methyl (5S,6Z,8E,10E,12R,14Z)-5-(benzoyloxy)-12-hydroxyicosa-6,8,10,14-tetraenedioate

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