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(2-naphthyl)methanol

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Origin: China

Cas No: 1592-38-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1592-38-7 Formula: C11H10O Molecular Weight: 158.19600

Description

β-Naphthylcarbinol is an intermediate in the synthesis of 2-Naphthylcarbapenem derivatives with broad spectrum antibiotics with enhanced potency against MRSA.

Basic Info

Chemical Name	(2-naphthyl)methanol
Synonyms	2-NaphthaleneMethanol; 2-(Hydroxymethyl)naphthalene; naphthalen-2-ylmethanol;
CAS No.	1592-38-7
Molecular Formula	C11H10O
Molecular Weight	158.19600
PSA	20.23000
LogP	2.33210

Properties

Appearance & Physical State	White crystalline solid
Density	1.151 g/cm3
Boiling Point	319.6ºC at 760 mmHg
Melting Point	79-83ºC
Flash Point	154ºC
Refractive Index	1.657
Storage Condition	Keep tightly closed. Store in a cool dry place.
Vapor Pressure	0.00014mmHg at 25°C

Safety Info

Safety Statements	S24/25
HS Code	2906299090
WGK Germany	3
Risk Statements	R11
Hazard Codes	Xi; C; F

Synthesis Route

2-Methylnaphthalene→(2-naphthyl)methanol+6-methylnaphthalene-1,4-dione
Formaldehyde+naphthalene→(2-naphthyl)methanol+(1-naphthyl)methanol
bis(2'-((2-naphthoyl)oxy)-[1,1'-binaphthalen]-2-yl) [1,1'-binaphthalene]-2,2'-dicarboxylate→(2-naphthyl)methanol+(+/-)-2,2'-bis(hydroxymethyl)-1,1'-binaphthyl

Precursor

2-Iodonaphthalene
tert-butyldimethyl(naphthalen-2-ylmethoxy)silane
carbon monoxide
methyl naphthalene-2-carboxylate

Downstream Product

N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(naphthalen-2-ylmethoxy)oxan-3-yl]acetamide
2-[(4-phenylphenyl)methyl]naphthalene
N,N-dimethyl-1-naphthalen-2-ylmethanamine
[(2R,3S,4R,5R,6R)-5-acetamido-3,4-diacetyloxy-6-(naphthalen-2-ylmethoxy)oxan-2-yl]methyl acetate

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