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2-Methoxybenzyl chloride

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Origin: China

Cas No: 7035-02-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 7035-02-1 Formula: C8H9ClO Molecular Weight: 156.60900

Description

1-(Chloromethyl)-2-methoxy-benzene is used in the synthesis of indole derivatives in the preparation of anti-cancer agents. Also used to synthesize potent and selective antagonists for the receptor CX3XR1 involved in the treatment of multiple sclerosis.

Basic Info

Chemical Name	2-Methoxybenzyl chloride
Synonyms	1-(chloromethyl)-2-methoxybenzene;
CAS No.	7035-02-1
Molecular Formula	C8H9ClO
Molecular Weight	156.60900
PSA	9.23000
LogP	2.43400

Properties

Appearance & Physical State	Clear colorless to yellow liquid
Density	1.125
Boiling Point	122-124ºC (26 mmHg)
Melting Point	28-30ºC
Flash Point	98ºC
Refractive Index	1.548-1.551
Storage Condition	Refrigerator (+4ºC)

Safety Info

Safety Statements	S26-S36/37/39-S45
HS Code	2909309090
WGK Germany	3
RIDADR	UN 3261
Risk Statements	R34
Hazard Codes	C

Synthesis Route

2-Methoxybenzyl alcohol→2-Methoxybenzyl chloride+4-Methoxybenzylchloride
hydrogen chloride+Formaldehyde→2-Methoxybenzyl chloride+4-Methoxybenzylchloride
2-Methoxybenzyl alcohol→2-Methoxybenzyl chloride

Precursor

2-Methoxybenzyl alcohol
2'-Hydroxyacetophenone
4-nitrobenzyl bromide
2-Methoxybenzaldehyde

Downstream Product

4-(2-methoxyphenyl)butanoic acid
chlorozinc(1+),1-methanidyl-2-methoxybenzene
magnesium,1-methanidyl-2-methoxybenzene,chloride
8-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLIC ACID

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