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2-HYDROXYMETHYL-1,4-BENZODIOXANE

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Origin: China

Cas No: 3663-82-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 3663-82-9 Formula: C9H10O3 Molecular Weight: 166.17400

Description

2-Hydroxymethyl-1,4-benzodioxane is a substituted benzodioxane with antihepatotoxic activity. 2-Hydroxymethyl-1,4-benzodioxane is used as an intermediate in the preparation of Guanoxan.

Basic Info

Chemical Name	2-HYDROXYMETHYL-1,4-BENZODIOXANE
Synonyms	2-Hydroxymethyl-1,4-benzodioxane; 2,3-dihydro-1,4-benzodioxin-3-ylmethanol; 1,4-Benzodioxin-2-methanol, 2,3-dihydro-; (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methanol; 1,4-Benzodioxane-2-methanol;
CAS No.	3663-82-9
Molecular Formula	C9H10O3
Molecular Weight	166.17400
PSA	38.69000
LogP	0.81870

Properties

Appearance & Physical State	white to light yellow crystalline powder
Density	1.213g/cm3
Boiling Point	286ºC
Melting Point	85-90ºC
Flash Point	123.8ºC
Refractive Index	1.544

Safety Info

RTECS	DF3660000
Safety Statements	S24/25
HS Code	2932999099
WGK Germany	3

Synthesis Route

methyl 2,3-dihydro-1,4-benzodioxine-3-carboxylate→2-HYDROXYMETHYL-1,4-BENZODIOXANE
Ethyl 1,4-Benzodioxane-2-carboxylate→2-HYDROXYMETHYL-1,4-BENZODIOXANE
2,3-Dibromo-1-Propanol+Catechol→2-HYDROXYMETHYL-1,4-BENZODIOXANE

Precursor

2,3-Dibromo-1-Propanol
methyl 2,3-dihydro-1,4-benzodioxine-3-carboxylate
Ethyl 1,4-Benzodioxane-2-carboxylate
Catechol

Downstream Product

3-(iodomethyl)-2,3-dihydro-1,4-benzodioxine
[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methanol
2,3-dihydro-1,4-benzodioxin-3-ylmethanamine
1,4-Benzodioxan

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